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Life Sciences

All Audio
Updated On: Nov 04, 2023
Total Stations: 629
Total Audio Titles: 28,232

Popular “Life Sciences” Stations

This Podcast Will Kill You This podcast might not actually kill you, but it covers so many things that can. Each episode tackles a different disease, from its history, to its biology, and finally, how scared you need to be. Ecologists and epidemiologists Erin Welsh and Erin Allmann Updyke make infectious diseases acceptable fodder for dinner party conversation and provide the perfect cocktail recipe to match.
Short Wave New discoveries, everyday mysteries, and the science behind the headlines — all in about 10 minutes. It's science for everyone, using a lot of creativity and a little humor. Join hosts Emily Kwong, Aaron Scott and Regina Barber for science on a different wavelength.If you're hooked, try Short Wave Plus. Your subscription supports the show and unlocks a sponsor-free feed. Learn more at plus.npr.org/shortwave
DNA Today: A Genetics Podcast The radio show/podcast educates the public on genetic and public health topics through event coverage, news stories, book/movie reviews, and interviews. Guest include genetic counselors, researchers, patient advocates and professors in the field of genetics.
Speaking of Psychology "Speaking of Psychology" is an audio podcast series highlighting some of the latest, most important and relevant psychological research being conducted today. Produced by the American Psychological Association, these podcasts will help listeners apply the science of psychology to their everyday lives.
Precision Evidence At the Precision Evidence Podcast, we go beyond the abstract of medical papers to find medical research relevant and meaningful to patients and healthcare professionals and separate the news from the fake news in medicine. Finding, evaluating, and using clinical trials with relevant outcomes for patients and Evidence-Based Medicine is the focus of the podcast’s analysis of medical papers, discussions, and interviews with stakeholders. Hosted by Dr. Kim Kristiansen, M.D., and JG Staal.
Twitter: @PrecisionEBM email us at [email protected]

Popular “Life Sciences” Playlists

The Human Body Listen to some of the best podcasts about anatomy and physiology here! Explore podcasts about how the human brain functions, the sensory organs, diseases, and much more. Vurbl Scientific Stories, News and Lessons
Highlights: Stem Cell Biology with Rebecca Lim (#1) Highlights from STEAM Powered's conversation with Rebecca Lim, Stem Cell Biologist, and related topics. STEAM Powered

All “Life Sciences” Audio

S5 E10: Food Infections and Food Intoxication: The Season Finale Often, the term food poisoning is used for both foodborne illnesses and foodborne intoxication. Today, I’m going to explain the difference between the two and talk about the burden that these illnesses have on societies, especially in the developing world. About 6.5 million in the US experience the effects of a foodborne pathogen at least once a year, but most of them go unreported since people think they just have the “stomach flu”. Newsflash, that was no flu, that was a foodborne pathogen. This is the final episode in Season 5, Restaurant Rogues, but don’t worry, I’ll be talking about more foodborne pathogens as time goes on. There are a LOT of them. Go check out this week’s episode to find out more about these illnesses and a few more. Cause of Death has a website! Come visit me at www.causeofdeath100secs.net. I also have an email address for the show at [email protected]. Feel free to interact with me in either place! Don’t forget that the next episode will be my Podversary episode, and I’ll be talking about what I call the Great Dilemma. The questions that I ask myself before I begin researching every episode that I put out. These are the questions that keep me up at night. It’s my hope that this episode will spark some discussion in the Facebook groups and on Twitter! Talk to me, folks! I’d love to hear from you! That episode will kick off Season 6, all about the diseases of wildlife. It’s called Who’s Who Outside of the Zoo. I’m so looking forward to that season! I’m going to be doing a special 100 Seconds to Midnight episode in Season 7. I’d like those of you who had experiences growing up during the Cold War to talk about those experiences. If you’d like to be a guest on the show, I can arrange that. If you’d rather just write your stories and send them in, that’s fine, too. I can read them. These stories are important, and they need to be heard. Please participate if you can. You can reach me on the website at www.causeofdeath100secs.net or you can email me at [email protected]. My Link Tree can be found at: https://linktr.ee/CauseofDeathpod The Difference Between Food Poisoning and Food Intoxication Show Notes: https://ask.usda.gov/s/article/What-is-the-difference-between-foodborne-illness-and-food-poisoning http://www.csun.edu/~cjh78264/foodsafety/pages/fbi1.html#:~:text=Infection%3A%20occurs%20when%20live%20bacterial,a%20toxin%20produced%20by%20bacteria. http://www.fightbac.org/ http://www.ces.ncsu.edu/depts/foodsci/agentinfo/org/index.html http://www.vdacs.state.va.us/foodsafety/index.html http://www.foodsafety.gov/ https://dchealth.dc.gov/service/food-borne-infections-and-intoxications <a href="https://epi.dph.ncdhhs.gov/cd/diseases/food.html" target="_blank"…
S6 E1: 100 Seconds to Midnight: 2nd Podversary: The Great Dilemma The Great Dilemma Show Notes: This is my second podversary. I’ve been in your ears and, hopefully, in your head for two years now, and I thought it important that you know about the things that go into each subject I talk about, whether it be an infectious disease that has the potential to kill millions if unleashed upon the population or a global crisis that looms over us. Every episode I struggle with questions. I research each topic carefully and I try to find solutions. This is something that I call the Great Dilemma. The questions, the answers and the solutions don’t come easy. I study them from several angles and sometimes, I don’t like the results. It’s 90 seconds to midnight and the questions that sometimes have no answers or don’t lead to solutions keep me up at night. Contact me at the website: www.causeofdeath100secs.net Check it out, leave a review, leave me a voicemail or an email. Look at the blog posts. Join my mailing list. There are so many ways to interact with me on that site that there’s no excuse not to! I also have a dedicated email for Cause of Death, you can reach me at [email protected]. Link Tree: https://www.linktr.ee.com/CauseofDeathpod There wasn’t any research for this episode, but it does refer to prior episodes. If you haven’t gone back, this would be a good time to do that. S1 E1: The Throwaway People: The Story of the AIDS Pandemic S3 E7: 100 Seconds to Midnight: Drip, Drip, Drip S3 E10: 100 Seconds to Midnight: Revisiting the HIV Pandemic and the Throwaway People S4 E1: 100 Seconds to Midnight: The History of the Doomsday Clock S4 E6: 100 Seconds to Midnight: Global Homelessness S5 E6: It’s 90 Seconds to Midnight and We Need to Talk There are several episodes mentioned that haven’t come out yet, too, so be watching for those! Darkcast Network – Promo by Yours Truly Support my sponsors! It ensures that Sweet Pea can eat! This month’s sponsors are FITAID and Codex. FITAID is a natural energy drink that contains several vitamins and minerals, but no artificial sweeteners. I’ve been drinking it after lunch when I need a little push to get me through the rest of my day at work. You can find FITAID products at https://www.drinkfitaid.com/causeofdeath for 40% off your first order! I’m really excited to discover Codex. I’m not very good to my skin, and as I age, it’s starting to show. Codex has really helped my skin repair from the damage that I’ve done to it over the years. You can find the Codex products here: https://www.codexlabscorp.com/ Use promo code: CauseofDeath20 for 20% off your first order. The True Crime and Paranormal Podcast Festival is coming up from August 25th to the 27th in Austin, Texas and I’ll be there representing another podcast that I’m heavily involved with. Stop by the True Consequences booth and meet Eric Carter-Landin and I! Get your tickets to the True Crime and Paranormal Podcast Festival at https://www.truecrimepodcastfestival.com Use promo code: Consequences for 15% off your ticket Podcast Promos: Horrifying History Rogue Darkness Music: Time Off by Damma Beatz You can reach me on: Instagram @causeofdeathpodcast FB: @CauseofDeath Twitter: @CauseofDeath10 TikTok: @causeofdeath100secs Please don’t forget to rate and review on any of the platforms found here: Apple Podcasts, Spotify and Podchaser: <a href="https://www.podchaser.com/podcasts/cause-of-death-1855050" target="_blank" rel="noreferrer…
Renewing This Old Brain – Dr. Jean Hebert As we age, the brain undergoes changes that lead to various disorders that affect physical ability and mental acuity. There are many processes at play, ranging from alterations in the extracellular environment, to accumulation of deleterious proteins, to a breakdown in connections between neurons. Can these processes be reversed?  Dr. Jean Herbert from the Albert Einstein School of Medicine has led efforts to reconstitute brain function through use of stem cells. Current steps in animal models may one day contribute to human therapies.
Kerstin Hellwig on family planning considerations in MS Kerstin Hellwig (Ruhr University Bochum, Bochum, Germany) discusses family planning considerations in multiple sclerosis. This Review is published in the April issue of The Lancet Neurology.
Karen Duff and Connor Langworth-Green on tauopathies and chronic inflammation Karen Duff and Connor Langworth-Green (University College London, London, UK) discuss tauopathies and the chronic effects of inflammation on this group of disorders. Their Personal View on this topic is published in the May issue of The Lancet Neurology.Read the Personal View here:Chronic effects of inflammation on tauopathies
The Scourge of Parkinson's Disease In this episode, we explore Parkinson's disease (PD), which is the second most common neurodegenerative disorder of aging after Alzheimer's disease, and the most common movement disorder. It affects approximately 1 million people in the United States, and it is estimated that 60,000 new cases are diagnosed each year. Worldwide more than 10 million people suffer from PD.  We described the disease in a patient story, discussed its epidemiology, causal pathways including genetics, signs and symptoms, medical and invasive treatments, prevention and future trends in research.  For more reading, here are some references:  Bloem, Bastiaan R., Michael S. Okun, and Christine Klein. "Parkinson's disease." The Lancet 397.10291 (2021): 2284-2303. Ascherio, Alberto, and Michael A. Schwarzschild. "The epidemiology of Parkinson's disease: risk factors and prevention." The Lancet Neurology 15.12 (2016): 1257-1272. Chen, Honglei, et al. "Consumption of dairy products and risk of Parkinson's disease." American journal of epidemiology, 165.9 (2007): 998-1006. Warnecke, Tobias, et al. "Gastrointestinal involvement in Parkinson’s disease: pathophysiology, diagnosis, and management." npj Parkinson's Disease 8.1 (2022): 31. Follow us: To participate in the weekly NEURO Science Club and join the discussions about the latest on brain health, join the NEURO Academy: NEUROacademy.com Follow us on social media: Instagram: The Brain Docs @thebraindocs Facebook: The Brain Docs TikTok: @thebraindocs Website: TheBrainDocs.com
Vigilance Leads to Long-Term Success Lionhearted Dentists with Dr. Steve Rasner no. 222 There can be no fear of communication in your office. Letting things go can be detrimental to your office.    Email [email protected] with any questions or comments you may have, as well as topics for discussion.   Other places you can connect with Dr. Rasner:   On the web here https://rasnerinstitute.com/ On Facebook here https://www.facebook.com/RasnerInstitute/   and here https://www.facebook.com/DrRasner  On Instagram here https://www.instagram.com/stevenl.rasner/?hl=en  And on Twitter here https://twitter.com/RasnerInstitute  He also runs a Facebook group for dentists who wish to remain independent here Lionhearted: Clinicians Who Won't Quit.
Episode 72: Special Regions in the Lower Limb There are some special areas in the upper and lower limb that can really help you quickly identify the structures that are there. You just need to find a few key structures and the rest falls into place. Join me so you can jumpstart you recognition on an upcoming test. Today, let’s talk about some special areas in the lower limb.To learn more about Amino Co and get 30% off with the discount code ANATOMY, go to aminoco.com/ANATOMYTo get all the episodes of the podcast, go to https://anatomyonthego.supercast.com/Support this podcast at — https://redcircle.com/anatomy-on-the-go/donations
Recharging in nature This week, in partnership with BMW, we're "recharging in nature" – discovering how stepping out into wild country replenishes our wellbeing batteries. But there's a disconnect for drivers of electric vehicles: many of the national parks are very much "off grid", paradoxically preventing those doing their bit for environmentally-friendly motoring with an electric car from benefiting. Luckily there's also a new initiative to power up national parks and benefit biodiversity… Like this podcast? Please help us by supporting the Naked Scientists
China hides Covid data, the problem with pain In the news, tech experts call for AI slowdown, monkeys fail to grasp magic tricks which require opposable thumbs to pull off, and why the WHO wants China to release information on the origin of Covid. Plus, according to one study, as many as 44 percent of the population suffer from chronic pain. The difficulty is, we experience pain in many different ways, making it notoriously hard to find treatments. We'll look into the possible causes of long term pain, and what scientists are doing to find solutions… Like this podcast? Please help us by supporting the Naked Scientists
Bonus Episode: Mantra Meditation This is a special, bonus episode brought to you in partnership with E.ON Next. If you've just been listening to our conversation with climate psychologist Patrick Kennedy-Williams, you'll know that they've created an audio toolkit for when eco-anxiety gets the better of you. We have part of it – a mindfulness meditation to boost well-being – for you here. For more of these resources search powerupforchange, or visit eonnext.com/eco-anxiety Like this podcast? Please help us by supporting the Naked Scientists
Eco-anxiety: getting hot under the collar about climate change In this bonus edition, climate psychologist Patrick Kennedy-Williams introduces us to the concept of eco-anxiety, the very real phenomenon leaving people across the UK feeling stressed about the future and the frightening implications of climate change. In partnership with E.ON NEXT – the energy provider on a mission to tackle eco-anxiety – we discuss when eco-anxiety first began to make its presence felt, who is most affected and why, and what we can all do to help both ourselves and the environment… Like this podcast? Please help us by supporting the Naked Scientists
Solar power milestones and bird microbiomes The world crosses the threshold of 1 terawatt of energy produced from solar means, the parting gift left behind by birds meeting an unfortunate demise, and looking for exoplanets that have magnetic fields Like this podcast? Please help us by supporting the Naked Scientists
Taking a trip into a black hole Black holes are one of the most extreme things in the universe. Their gravitational pull is so strong, they can bend light and even time. So were you to find one and fall into it…what would happen? Like this podcast? Please help us by supporting the Naked Scientists
Aphids and Aphid-Transmitted Viruses Aphids are known for the destruction they can cause due to feeding damage. But they can also be responsible for transmitting harmful viruses into the crops. In this episode we hear from Dr. Lyndon Porter is a plant pathologist at USDA-ARS based in Prosser, Washington, Dr. Sean Prager is an associate professor of entomology at the University of Saskatchewan and Dr. Sanford Eigenbrode is a professor of entomology at the University of Idaho. There is a tremendous amount of collective knowledge in this group covering aphid-related topics including the development of genetic tolerance to the insect and resistance to the viruses. We also discuss aphid sampling and hosts, chemical options for management and other integrated pest management strategies.“We estimated a direct injury threshold, a level of aphid infestation that would justify a spray. And we had a second calculator that attempted to help growers who are concerned about the aphid as a vector of the virus, which is a different thing. In that case, we would say the nominal threshold is one aphid because it only takes an aphid that's prolific to feed for an hour and you have a sick plant.” – Dr. Sanford EigenbrodeLyndon says that giving growers real time data on aphid presence and aphid levels has been a critical step to helping with management of this pest and associated diseases. All three of our guests agree the long term goal is a combination of integrated pest management built upon a foundation of genetic tolerance to the pest and resistance to the diseases. This represents a really interesting area of research that combines entomology, pathology, plant breeding and several other areas of study. “If we can just get the associations between genetic elements and resistance, we can skip knowing exactly what those genes are coding for as long as we can track them into the breeding lines.” – Dr. Sanford Eigenbrode This Week on Growing Pulse Crops:Meet Dr. Lyndon Porter, a plant pathologist at USDA-ARS based in Washington, Dr. Sean Prager, an associate professor of entomology at the University of Saskatchewan, and Dr. Sanford Eigenbrode, a professor of entomology at the University of IdahoExplore the impact of aphids and the measures being taken to not only reduce the damage aphids cause by feeding but also reduce the impact of the viruses the aphids vectorDiscover the factors contributing to aphid spread and the monitoring proving to be significant in managing their impactLearn about the process towards developing genetic resistance to this pest and the tools being used to produce results quickerGrowing Pulse Crops Podcast is hosted by Tim Hammerich of the Future of Agriculture Podcast.
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Episode 3: From farm to pharma, meet Terumo’s CEO This episode of the Voices of Biotech – brought to you by the BioProcess Insider Expression Platform -brings you an in-depth conversation with Antoinette Gawin, CEO of Terumo Blood and Cell Technologies.
Gawin shares her personal experience of growing up within an immigrant farming community before entering the pharma space and climbing the career ladder. She talks about how people should not be afraid to show vulnerability in the workplace. Additionally, she discusses the importance of making sure all voices are heard, regardless of who the voices come from.
We discuss women in the life sciences space, diversity and inclusion, and how this cannot be seen as a task but must be part of your company culture to truly anchor value, employee wellbeing and successful performance. The conversation also delves into how there a perception that when a woman brings an idea to the space, there is still an aspect of risk associated with this.
Bacteria deceived us! Life is not simple Science advances in fits and starts, and it sometimes takes a detour onto a dead-end road. Bacteria represent one of those roads. Studying bacteria gave us a sense that we could easily figure out biology, that there was a direct connection between genes and behavior, and that life was simple. Granted, there was no other way to get started, but the study of bacteria slowed down our understanding of higher organisms in many ways. From the ‘one gene, one enzyme’ hypothesis to the thought that living systems can be reduced to a binary decision tree, many things about bacteria misled us and prevented science from seeing that the majority of the information in the genomes of higher organisms is in the non-coding DNA.

C-value paradox
G-value paradox
Transcription factors
Bathybius (on Creation.com)
One gene, one enzyme hypothesis
Lac operon
Boolean data
Pediatrics Research Roundup, Direct Admission to Hospitals – Ep. 153 In this episode Lewis First, MD, MS, FAAP, editor-in-chief of Pediatrics, is back for “First Up.” He offers a bird’s-eye view of what’s in the April issue of the journal. Hosts David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak with JoAnna Leyenaar, MD, PhD, MPH, author of a new policy statement on direct admission of children to hospitals. For resources go to aap.org/podcast.
Peep The Delightful Science Of Chickens When Tove Danovich decided to dabble in backyard chicken keeping, she embraced a tried and true journalistic practice — reading everything there is to find on the subject. In her search, she found plenty of how-to guides, but what she really wanted was to know more about the science. She wanted to understand their evolution and unique relationship with humans. "As I was reading more and as I was wanting this book that increasingly it seemed like it it just didn't exist. I wound up writing it instead," says Tove. Today, Aaron visits Tove in her chicken coop to talk about her recent book Under the Henfluence: Inside the World of Backyard Chickens and the People Who Love Them and to meet the chicken stars of Tove's Instagram account.Listen to Short Wave on Spotify, Apple Podcasts and Google Podcasts. Know of a new book we should feature on Short Wave? Drop us a line at [email protected].
Are Rats Running This Podcast? This week, New York City crowned Kathleen Corradi its first rat czar. The new position is part of a multipronged approach from city officials. Reporter and New Yorker Anil Oza called up rodentologists to understand — does their approach withstand the test of scientific research? We love hearing your musings and questions about the science in your everyday life. Reach us by emailing [email protected].
Where are the whales? Scientists find clues thousands of miles away Endangered North Atlantic right whales are disappearing from their native waters, a serious danger for a species with only 340 animals left. The mystery behind this change took NPR's climate reporter Lauren Sommer 2,000 miles away to the world's second-largest ice sheet, sitting on top of Greenland. On today's episode, Lauren takes Short Wave co-host Emily Kwong on an expedition to Greenland's ice sheet and then to the Gulf of Maine to break down the ripple effects of climate change. Reach the show by emailing [email protected].
Lessons in Environmental Health and Crisis Communications from the Ohio Train Derailment It’s been a couple months since the train derailment in East Palestine, Ohio, but many people still have questions about its environmental and health impacts. What do we know about the chemicals that were being transported on that train? What can we learn about crisis communications from this event? How concerned do we need to be about chemical exposure in general and how do we evaluate our risk? Download the latest episode of Public Health Out Loud to get answers from our local experts Dr. Mike Byrns, the principle environmental health risk assessment toxicologist at the Rhode Island Department of Health (RIDOH; Joseph Wendelken, the public information officer at RIDOH; and Mike Healey, the public information officer at the Rhode Island Department of Environmental Management.
Rehabilitate Anywhere: Exploring the Benefits and Challenges of Telerehabilitation Register now for ATS 2023 in Washington, D.C.Get ready for a series of dynamic scientific programming with presentations covering the basic sciences, research breakthroughs and clinical treatment!In this podcast, we explore the groundbreaking world of tele-rehabilitation and how it is transforming the healthcare industry. Tele-rehabilitation is the practice of providing rehabilitation services to patients in remote locations through the use of technology. We discuss the benefits of tele-rehabilitation, including increased accessibility, convenience, and cost-effectiveness for patients. Our experts delve into the various applications of tele-rehabilitation, including its use in pulmonary rehabilitation, neurological conditions, and eduation.



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Attunement, Portal to Ascension Are you entangled in your own negativity, or are you present to Source Consciousness? How to free yourself from your limiting beliefs. Join me as I tell stories.



Send in a voice message: https://podcasters.spotify.com/pod/show/nora-s8/message



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Reprogramming the mind with NLP As we dive into the language of the cosmos, expanding our vocabulary to have a greater understanding of things is a must. Join me in this discussion on how we program our minds with language.



Send in a voice message: https://podcasters.spotify.com/pod/show/nora-s8/message



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Conversational expansion When you choose to expand your consciousness, miracles happen. I expanded my love and became the bridge to a new timeline. What hurts more: 1) maintaining a bad situation and feeling bad while being in it or 2) making a purposeful change and choosing to expand yourself?



Send in a voice message: https://podcasters.spotify.com/pod/show/nora-s8/message
Looking at Lyme Podcast Survey! We are approaching the end of Season 4, and Looking at Lyme is looking for your feedback in our new podcast survey! We have interviewed so many interesting guests over the past few years: it’s hard to believe that we are finishing up our 4th Season with our 55th podcast! We want to hear from you. We want to know what content you are enjoying and ideas about who we might interview in future episodes. Please fill out the survey and let us know! Take our survey: www.canlyme.com/survey/
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Nasal blood supply & Epistaxis This week let's re-enter the nasal cavity & focus our attention on its blood supply. Why does the nose have such a significant blood supply? What vessels contribute to it? And what happens when it breaks? 
The terms covered this week are Little's area or Kiesselbach's plexus & Woodruff's plexus. The blood vessels with the mnemonic L.E.G.S, Labial (Superior), Ethmoids (anterior & posterior), Greater palatine & Sphenopalatine arteries.
A medical advocate's role in the COVID ICU In this episode, guest Sara L. Merwin, co-author of The Informed Patient: A Complete Guide to a Hospital Stay, shares her experience helping a family navigate their loved one's hospital stay during the height of the COVID pandemic. With visitors not allowed in the ICU, Sara served as a remote advocate, helping the family communicate with the care team and providing guidance on getting the best outcomes for their loved one. She discusses the importance of patient advocacy and how having a helping hand can make a significant difference in navigating the complex hospital ecosystem, especially in the midst of a pandemic. Sara L. Merwin is the co-author of The Informed Patient: A Complete Guide to a Hospital Stay. She shares her story and discusses the KevinMD article, "The isolation of the COVID ICU: the need for patient advocates." The Podcast by KevinMD is brought to you by the Nuance Dragon Ambient eXperience. With a growing physician shortage, increasing burnout, and declining patient satisfaction, a dramatic change is needed to make health care more efficient and effective and bring back the joy of practicing medicine. AI-driven ambient clinical intelligence promises to help by revolutionizing patient and provider experiences with clinical documentation that writes itself. The Nuance Dragon Ambient eXperience, or DAX for short, is a voice-enabled, ambient clinical intelligence solution that automatically captures patient encounters securely and accurately at the point of care. Physicians who use DAX have reported a 50 percent decrease in documentation time and a 70 percent reduction in feelings of burnout, and 83 percent of patients say their physician is more personable and conversational. Rediscover the joy of medicine with clinical documentation that writes itself, all within the EHR. VISIT SPONSOR → https://nuance.com/daxinaction SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended GET CME FOR THIS EPISODE → https://earnc.me/cEy0nT Powered by CMEfy.
From community to corporation: the transformation of primary care In this podcast episode, we have Michael Fine, a family physician and author of On Medicine as Colonialism, sharing his insights on the changing landscape of primary care. He reflects on his experience of practicing in a time when family doctors lived in and supported the communities they served. However, today, primary care has become a huge economic engine generating profits for corporations, and it has led to what he calls "primary care colonialism." Michael discusses how this kind of colonialism removes the relationships that are essential for sustaining communities, leading to a denuded society devoid of its unique identity and history. He questions whether this is the primary care and medicine we want and suggests the need to change it from the bottom up. Michael Fine is a family physician and author of On Medicine as Colonialism. He shares his story and discusses his KevinMD article, "Primary care colonialism: the impact of profit-driven health care on communities." The Podcast by KevinMD is brought to you by the Nuance Dragon Ambient eXperience. With a growing physician shortage, increasing burnout, and declining patient satisfaction, a dramatic change is needed to make health care more efficient and effective and bring back the joy of practicing medicine. AI-driven ambient clinical intelligence promises to help by revolutionizing patient and provider experiences with clinical documentation that writes itself. The Nuance Dragon Ambient eXperience, or DAX for short, is a voice-enabled, ambient clinical intelligence solution that automatically captures patient encounters securely and accurately at the point of care. Physicians who use DAX have reported a 50 percent decrease in documentation time and a 70 percent reduction in feelings of burnout, and 83 percent of patients say their physician is more personable and conversational. Rediscover the joy of medicine with clinical documentation that writes itself, all within the EHR. VISIT SPONSOR → https://nuance.com/daxinaction SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended GET CME FOR THIS EPISODE → https://earnc.me/HCr5pc Powered by CMEfy.
Psychological safety: the unspoken key to health care success In this episode, we are joined by clinical psychologist and health systems leadership consultant, Nicola F. De Paul, to discuss the importance of psychological safety in health care environments. Nicola shares her personal experience of addressing psychological safety concerns at an academic medical center and the impact of implementing changes in the training environment. We explore the role of health care leaders in creating psychologically safe spaces, the need for self-reflection, and the importance of elevating diverse voices to create a supportive environment for all employees. Tune in as we dive into creating resilient health care systems where everyone thrives and patient care is safer. Nicola F. De Paul is a clinical psychologist and a health systems leadership consultant. She shares her story and discusses her KevinMD article, "Leaders who elevate diverse employees create psychological safety." The Podcast by KevinMD is brought to you by the Nuance Dragon Ambient eXperience. With a growing physician shortage, increasing burnout, and declining patient satisfaction, a dramatic change is needed to make health care more efficient and effective and bring back the joy of practicing medicine. AI-driven ambient clinical intelligence promises to help by revolutionizing patient and provider experiences with clinical documentation that writes itself. The Nuance Dragon Ambient eXperience, or DAX for short, is a voice-enabled, ambient clinical intelligence solution that automatically captures patient encounters securely and accurately at the point of care. Physicians who use DAX have reported a 50 percent decrease in documentation time and a 70 percent reduction in feelings of burnout, and 83 percent of patients say their physician is more personable and conversational. Rediscover the joy of medicine with clinical documentation that writes itself, all within the EHR. VISIT SPONSOR → https://nuance.com/daxinaction SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended GET CME FOR THIS EPISODE → https://earnc.me/NTYIXf Powered by CMEfy.
United by medicine: a journey of friendship, success, and the power of character Join us in this episode as we dive into the incredible bond between Sharyar Baradaran, a periodontist, and Arya Shamie, an orthopedic surgeon. Despite their different religious backgrounds and specializations, these two childhood friends from Iran have come a long way to excel in their respective fields and become thought leaders in the medical community. In this candid conversation, they share their inspiring journey of immigration, success, and the importance of valuing people based on character rather than religious or financial status. Get ready to be inspired as they reveal how they came to live just a block away from each other by pure coincidence. Listen in as they reflect on the current situation in Iran, their individual faiths, and how their friendship has blossomed despite their differences. This episode serves as a powerful reminder of the importance of embracing diversity and the true keys to success in life and medicine. Sharyar Baradaran is a periodontist. Arya Shamie is an orthopedic surgeon. They share their stories and discuss the KevinMD article, "6 tips to make a lasting impact in the medical field." The Podcast by KevinMD is brought to you by the Nuance Dragon Ambient eXperience. With a growing physician shortage, increasing burnout, and declining patient satisfaction, a dramatic change is needed to make health care more efficient and effective and bring back the joy of practicing medicine. AI-driven ambient clinical intelligence promises to help by revolutionizing patient and provider experiences with clinical documentation that writes itself. The Nuance Dragon Ambient eXperience, or DAX for short, is a voice-enabled, ambient clinical intelligence solution that automatically captures patient encounters securely and accurately at the point of care. Physicians who use DAX have reported a 50 percent decrease in documentation time and a 70 percent reduction in feelings of burnout, and 83 percent of patients say their physician is more personable and conversational. Rediscover the joy of medicine with clinical documentation that writes itself, all within the EHR. VISIT SPONSOR → https://nuance.com/daxinaction SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended GET CME FOR THIS EPISODE → https://earnc.me/IaTLk9 Powered by CMEfy.
Healing the healer: How physicians can overcome the struggle of caring Join us in this insightful podcast episode as we welcome Karen Leitner, an internal medicine-pediatrics physician and life coach, to discuss the unique challenges physicians face when their loved ones need medical care. Karen shares her personal experiences and sheds light on the logistical, internal, and resistance-related obstacles that can make it difficult for doctors to help their family members in the same way they do for their patients. Learn how embracing self-compassion can ease the emotional burden and navigate the complexities of being both a physician and a loved one. Tune in for a heartfelt conversation on finding balance, building understanding, and fostering self-compassion in the face of these difficult situations. Karen Leitner is an internal medicine-pediatrics physician and life coach. She shares her story and discusses her KevinMD article, "When a loved one is a patient: Navigating the emotional burden for physicians." The Podcast by KevinMD is brought to you by the Nuance Dragon Ambient eXperience. With a growing physician shortage, increasing burnout, and declining patient satisfaction, a dramatic change is needed to make health care more efficient and effective and bring back the joy of practicing medicine. AI-driven ambient clinical intelligence promises to help by revolutionizing patient and provider experiences with clinical documentation that writes itself. The Nuance Dragon Ambient eXperience, or DAX for short, is a voice-enabled, ambient clinical intelligence solution that automatically captures patient encounters securely and accurately at the point of care. Physicians who use DAX have reported a 50 percent decrease in documentation time and a 70 percent reduction in feelings of burnout, and 83 percent of patients say their physician is more personable and conversational. Rediscover the joy of medicine with clinical documentation that writes itself, all within the EHR. VISIT SPONSOR → https://nuance.com/daxinaction SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended GET CME FOR THIS EPISODE → https://earnc.me/EqXmGQ Powered by CMEfy.
Find shoval on Twitter (https://twitter.com/MiyaraShoval)
Read the full preprint -> https://www.biorxiv.org/content/10.1101/2023.01.01.522422v1 
This episode was produced by Jonny C” id=”9t5ZacfRe1n” vid=”9t5ZacfRe1n” id-for-player=”9t5ZacfRe1n” link=”/listen/fibrosis-its-hot-and-its-cold-9t5ZacfRe1n/” is-authorized=”false” custom-styles=”margin: 0 24px 24px 0;”>
Fibrosis; It's hot and it's cold This week we discuss hot and cold fibrosis with Shoval Miyara, a PhD student at the Weizmann Institute of Science. 
Find shoval on Twitter (https://twitter.com/MiyaraShoval)
Read the full preprint -> https://www.biorxiv.org/content/10.1101/2023.01.01.522422v1 
This episode was produced by Jonny Coates and edited by Camila Valenzuela. 
If you enjoyed this show then hit that subscribe button and leave a review (on Apple Podcasts or Spotify). If you love what we are trying to do then buy us a coffee https://www.buymeacoffee.com/preprints! Any contribution is greatly appreciated.
For the latest podcast news and updates follow us on Twitter @MotionPod, Instagram @Motion_Pod or visit our website; www.preprintsinmotion.com.
Find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) & Camila (@Kamo_Valenzuela). Generously supported by ASAPbio (https://asapbio.org | @asapbio_).
Lessons from a Medtech Entrepreneur: Ram Konduru on Fostering Teamwork and Personal Growth in Leadership The FDA Group's CEO, Nick Capman sits down with Ram Konduru, CEO of PrimeSoft Inc (North America & Europe) and Co-Founder of Coherence Health. Ram discusses his experience in leadership and management, highlighting the importance of having a common purpose and goal for a team. Ram and Nick also discuss the need for leaders to create strong bonds within their teams, provide opportunities for team members to bond, and be humble and relatable.
Other discussion points include:
» Ram’s personal growth journey as a leader, the impact of his mentors on his development, and the importance of self-reflection, practice, and having a genuine belief in the company's mission. 
» The idea that money is a byproduct of value creation.
» The challenges of being a modern leader and manager—and the importance of staying curious and maintaining a learning attitude.
» Life-impacting questions.
» The importance of personal relationships and reflecting on one’s actions.
» A few book recommendations.
Who is The FDA Group? The FDA Group helps life science organizations rapidly access the industry's best consultants, contractors, and candidates. Our resources assist in every stage of the product lifecycle, from clinical development to commercialization, with a focus in Quality Assurance, Regulatory Affairs, and Clinical Operations. https://www.thefdagroup.com/
Discussion points include:
» The three classifications of medical devices and the” id=”k3V9gO2XRm” vid=”k3V9gO2XRm” id-for-player=”k3V9gO2XRm” link=”/listen/a-deep-dive-into-medical-device-regulatory-strategy-with-regulatory-attorney-christine-p-bump-k3V9gO2XRm/” is-authorized=”false” custom-styles=”margin: 0 24px 24px 0;”>
A Deep Dive into Medical Device Regulatory Strategy with Regulatory Attorney Christine P. Bump The FDA Group's CEO, Nick Capman, sits down with Regulatory Attorney Christine P. Bump to discuss the current regulatory landscape for medical devices and the importance of developing a thoughtful regulatory strategy.
Discussion points include:
» The three classifications of medical devices and the various regulatory submission types — each with different risk levels, required data, costs, and approval timelines.
» The costs associated with FDA approval.
» Why it's important to craft a regulatory strategy early, even at the product concept stage, to determine device functionality and anticipate FDA requirements.
» The challenges that the rapidly evolving nature of software, algorithms, and AI present for the FDA's traditional device paradigm.
» The benefits of pre-submission meetings with the FDA, which provide valuable feedback and insights to streamline the submission process.
» The differences between regulatory attorneys and consultants.
» The common pitfalls for companies navigating the FDA approval process, such as insufficient budgeting and lack in-house expertise.
» The importance of planning well in advance and adjusting operational goals to align with regulatory requirements.
» The importance of understanding product claims to avoid regulatory complications.
Christine is a regulatory attorney with more than 15 years of experience developing and implementing FDA strategies for cutting-edge technologies. As the founder of Penn Avenue Law & Policy, she focuses on devices, software as a medical device, digital health, diagnostics, wellness, genetics and genomics, and advertising and promotion. She advises CEOs, scientists, and teams of all levels regarding regulatory pathways, clinical investigations, premarket submissions, pre- and postmarket compliance, and promotional issues. She counsels a variety of clients, including start-ups, national and multi-national corporations, venture capital groups, and portfolio companies on navigating the FDA process. https://www.pennavenuelaw.com/
Who is The FDA Group? The FDA Group helps life science organizations rapidly access the industry's best consultants, contractors, and candidates. Our resources assist in every stage of the product lifecycle, from clinical development to commercialization, with a focus in Quality Assurance, Regulatory Affairs, and Clinical Operations. https://www.thefdagroup.com/
Pediatric Podcast Pearls, "Hyperbilirubinemia Update: Review of the AAP 2022 Clinical Practice Guideline Revision", David Sink, MD Familiarize learners with the significant changes in the 2022 AAP Hyperbilirubinemia Clinical Practice Guidelines Revision for Newborn Infants Greater than 35 Weeks specifically regarding risk assessment bilirubin monitoring hyperbilirubinemia treatment and post-discharge follow up.
4.4.23, Pediatric Grand Rounds, "Honorary Childhood Trauma & Violence: Childhood Exposure to Trauma: A Personal Odyssey", Drs. Leon Chameides & Melissa Santos Discuss the story of my survival under German and Russian occupations.Relate my experiences to the effects of childhood trauma today.Define childhood trauma.Describe those most at risk.Identify strategies you can implement in your practice to be trauma informed.
4.11.23, Pediatric Grand Rounds, "Disparities in Access to Health Care and Youth Sports in Pediatric Athletes.", Allison Crepeau, MD Review basic terminology related to describing barriers to health care.Describe some of the barriers for patient access to orthopedics and sports medicine.Describe some options to improve access for all patients.
Lenalidomide and genetic profiling in myeloma, T-cell immunotherapy upregulates AML cell MHC-class II, and young fecal microbiota rejuvenate HSCs In this week’s episode we will review optimizing the value of post-transplant lenalidomide maintenance in multiple myeloma. Next, T-cell immunotherapies targeting AML antigens upregulate MHC Class II expression on AML cells. Finally, young bugs rejuvenate old blood: transplanting fecal microbiota from younger mice into older mice improved hematopoietic stem cell function and restored lymphoid differentiation potential.
DDW Highlights: 3 April 2023 The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates.  As March draws to a close, this week’s key announcements have demonstrated the breadth of international approaches to tackling cancer, with vaccines, proenzymes, immunotherapies and antibody-based treatments all currently under investigation around the world.  You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts.
Data integrity and the value of the cloud This is the latest episode of the free DDW podcast, “Data integrity and the value of the cloud”. It covers two articles written for the exclusive DDW & SLAS2022 supplement published in Volume 23, Issue 1 – Winter 2021/22 of DDW. They are called “The concept of data integrity” and “Remote working: when the cloud meets the lab”. In the first article, Sophia Ktori outlines the importance of data integrity in labs at every stage of product development and manufacturing on behalf of SiLA. In the second article, Toby Blackburn, who runs business development and strategy at Emerald Cloud Lab (ECL) shares insight into is main responsibility to help clients, and the industry, understand the technology, how it can benefit them, and what the future lab looks like. You can also find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts.
DDW Highlights: 11 April 2023 The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates.  The headlines this week have revealed a high level of clinical trial activity taking place internationally. In just the last few days, new clinical trials in colorectal cancer, osteoarthritis, and brain cancer have been launched, and positive early-stage results have been reported from ongoing trials in heart failure and solid tumours.  You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts.
Follow up on Being a Warrior Remain dedicated to the values that make up who you are. Hear Dr. Rasner discuss the importance of having the significant other of the patient there when presenting cases so major decisions can be made efficiently.    Email [email protected] with any questions or comments you may have, as well as topics for discussion.   View the full video of this podcast on our YouTube channel: https://www.youtube.com/c/RasnerInstitute    Other places you can connect with Dr. Rasner:   On the web here https://rasnerinstitute.com/ On Facebook here https://www.facebook.com/RasnerInstitute/   and here https://www.facebook.com/DrRasner  On Instagram here https://www.instagram.com/stevenl.rasner/?hl=en  And on Twitter here https://twitter.com/RasnerInstitute  He also runs a Facebook group for dentists who wish to remain independent here Lionhearted: Clinicians Who Won't Quit.
The Obvious Solution A Lionhearted Dentist is a leader at all times. Having a cohesive team starts with regular, organized morning meetings. If communication falls apart, everything falls apart.    Email [email protected] with any questions or comments you may have, as well as topics for discussion.   View the full video of this podcast on our YouTube channel: https://www.youtube.com/c/RasnerInstitute    Other places you can connect with Dr. Rasner:   On the web here https://rasnerinstitute.com/ On Facebook here https://www.facebook.com/RasnerInstitute/   and here https://www.facebook.com/DrRasner  On Instagram here https://www.instagram.com/stevenl.rasner/?hl=en  And on Twitter here https://twitter.com/RasnerInstitute  He also runs a Facebook group for dentists who wish to remain independent here Lionhearted: Clinicians Who Won't Quit.
Christian Behn (CEM) discuss the evolution of SPOT Synthesis to generate
peptide libraries. They also correct some misinformation and bring to light the
ease and utility of applying SPOT arrays to biologica” id=”5t212rZQ2pi” vid=”5t212rZQ2pi” id-for-player=”5t212rZQ2pi” link=”/listen/spot-synthesis-and-peptide-arrays-5t212rZQ2pi/” is-authorized=”false” custom-styles=”margin: 0 24px 24px 0;”>
SPOT Synthesis and Peptide Arrays In this episode of Exploration Science, Drs. Ronald Frank (AIMS Scientific Products GmbH) and
Christian Behn (CEM) discuss the evolution of SPOT Synthesis to generate
peptide libraries. They also correct some misinformation and bring to light the
ease and utility of applying SPOT arrays to biological studies.  

Watch on YouTube: https://youtu.be/MBJFIygXDRg

Correction: The founding of AIMS company was in 1998, not 1989.
 
See the links and references below for some examples of SPOT applications:
AIMS Scientific Products http://www.aims-scientific-products.de/index.php
CEM MultiPep: https://cem.com/multipep2
Clemens Schulte, Vladimir Khayenko, Amit Jean Gupta, Hans Michael Maric. Low-cost
synthesis of peptide libraries and their use for binding studies via
temperature-related intensity change. STAR Protocols. Volume 2, Issue 3,
2021, 100605. https://doi.org/10.1016/j.xpro.2021.100605.
 Melder FTI, Lindemann P, Welle A, Trouillet V, Heißler S, Nazaré M, Selbach M. Compound
Interaction Screen on a Photoactivatable Cellulose Membrane (CISCM) Identifies
Drug Targets. ChemMedChem. 2022 Oct 6;17(19):e202200346. doi:
10.1002/cmdc.202200346. Epub 2022 Sep 20. PMID: 35867055; PMCID: PMC9826412.
 Mohammed El-Mowafy, Ursula Bilitewski. Identification of possible Ser/Thr/Tyr
phosphorylation sites in the fungal histidine kinase CaNik1p by peptide array
technique. Bulletin of Faculty of Pharmacy, Cairo University. Volume 56,
Issue 1, 2018, Pages 68-72. https://doi.org/10.1016/j.bfopcu.2018.03.007.
 Moreno-Yruela, C., Bæk, M., Vrsanova, AE. et al. Hydroxamic acid-modified peptide
microarrays for profiling isozyme-selective interactions and inhibition of
histone deacetylases. Nat Commun 12, 62 (2021). https://doi.org/10.1038/s41467-020-20250-9.
 Meyer et al., Mutations in Disordered Regions Can Cause Disease by Creating Dileucine
Motifs. Cell (2018), https://doi.org/10.1016/j.cell.2018.08.019.
Rebollo, A., Fliedel, L., Tuffery, P., PEPscan: A Broad-Spectrum Approach for the
Characterization of Protein-Binder Interactions? Biomolecules 2022, 12,
178. https://doi.org/10.3390/
Rosie M. Jarrald, Aw W. Liang Alvin, Andrea E. Rawlings, Masayoshi Tanaka, Mina Okochi,
and Sarah S. Staniland. Systematic Screening and Deep Analysis of CoPt
Binding Peptides Leads to Enhanced CoPt Nanoparticles
Chief Operating Officer & Co-Founder of Monod Bio discusses the next
generation of clinical diagnostics and how the company is transforming point of
care for patients. Tune in and learn how scientists at Monod Bio are driving
diagnostic inno” id=”5GZvHtYYBXY” vid=”5GZvHtYYBXY” id-for-player=”5GZvHtYYBXY” link=”/listen/de-novo-protein-biosensors-transforming-point-of-care-5GZvHtYYBXY/” is-authorized=”false” custom-styles=”margin: 0 24px 24px 0;”>
De Novo Protein Biosensors: Transforming Point of Care In this episode of Exploration Science, Dr. David Shoultz,
Chief Operating Officer & Co-Founder of Monod Bio discusses the next
generation of clinical diagnostics and how the company is transforming point of
care for patients. Tune in and learn how scientists at Monod Bio are driving
diagnostic innovation through de novo protein design and
deploying lucCage technology. This platform is based on research conducted
by Dr. David Baker and scientists at the University of Washington Institute for
Protein Design to generate artificial luciferases with optimized size,
stability, substrate specificity, and photophysical properties.
Intelligently Navigating the Peptide Chemical Space In this episode of ExplorationScience, Dr. Jonathan Steckbeck, the founder and CEO of Peptilogics, discusses the company's approach to peptide drug discovery. Tune into this episode to learn how partnering biology with machine learning is guiding the intelligent navigation of peptide chemical space to develop next-generation therapeutics.
The Twende Out in Nairobi – with the Global Listening Project In the aftermath of COVID lockdowns, how have health, career and life opportunities changed for Kenyan teenage girls & young women? ”Twende (let’s go) Out” with Heidi Larson’s Global Listening Project in Nairobi to understand how changing social norms are helping – and hindering the country’s post-COVID generation of young people. Guests:Lilian Otiso, Executive Director, LVCT HealthFarida Nzilani, Digital Manager, Shujaaz Inc.Ante Neosoul, Musician, DJ, TV and Radio Host, Podcaster, @antoneosoulLinks:https://listeningproject.globalhttps://lvcthealth.orghttps://www.shujaazinc.comhttps://one2onekenya.orghttps://nsdcc.go.kehttps://www.vaccineconfidence.orghttps://orb-international.comhttps://www.researchplusafrica.com/index.htmlhttps://africori.to/welcome2mysouldeluxehttps://podcasts.apple.com/us/podcast/mantalk-ke/id1541453976On-site production and direction by Nick Mutuma and team at Giraffe Africa Productions Ltd. @shotbygiraffeThanks also to https://nairobistreetkitchen.comAnd special shout to our favorite social media influencer Shujaaz’s @TheDJBoyie #HIV #socialnorms #teenagegirls #gendernorms #sexualreproductivehealth #COVID #unplannedpregnancy#familyplanning #genderbasedviolence–Youtube video version:https://youtu.be/n5L5iT24j7E
Chuck and Chris Talk JBJS What's New in Hand Surgery Season 4, Episode 9.  Chuck and Chris take a deep dive into Deborah Bohn's What's New in Hand Surgery in JBJS.  The article covers key new articles into our favorite research topics in hand surgery.  This is Part 1 of a two part series.JBJS 2023; 105:428-34Subscribe to our newsletter:  https://bit.ly/3iHGFpDSee www.practicelink.com/theupperhand for more information from our partner on job search and career opportunities. Please complete NEW Survey: bit.ly/3X0Gq89As always, thanks to @iampetermartin for the amazing introduction and conclusion music.Complete podcast catalog at theupperhandpodcast.wustl.edu.
3.4 Passive sensory characteristics identified Explaining how some children and adults with SPD may be actively aware of the sensory input they are processing or passively aware and what this means.
Ancient Genes and Trust in New Tech This month, the genetic variants inherited from millions of years back that protect from disease but can cause illnesses; also, signs that we trust human-sourced information more than what a computer might say, how the whiff of a female can make some mice live longer, what bird's eggs can tell us about dinosaurs, and how taking a leaf out of "doughnut economics" can help academics combat the climate crisis… Get the references and the transcripts for this programme from the Naked Scientists website
Seroprevalence and Molecular Detection of Anaplasma marginale-infected Beef Herds in Georgia, USA AABP Executive Director Dr. Fred Gingrich is joined by past AABP Board of Directors member from District 3, Dr. Lee Jones. Jones is an associate professor at the University of Georgia in the Beef Production Medicine department. Jones was the first author on the paper titled “Seroprevalence and molecular detection of Anaplasma marginale-infected beef herds in Georgia, USA”, which was published in The Bovine Practitioner Volume 56 Number 2 (2022). We review the transmission, clinical signs, and diagnostic tests for bovine anaplasmosis. The objective of the study was to conduct and compare seroprevalence and molecular detection of Anaplasma marginale-infected beef herds in Georgia and to identify herd risk factors associated with A. marginale-positive herds. Blood samples were collected from 1,059 adult beef cattle (≥ 2 years) from 33 herds. Overall, 8.12% of cattle and 42% of herds were cELISA antibody-positive. Seventy-seven percent of plasma samples from a subset of corresponding seropositive samples (n = 73) were PCR-positive. Jones reviews the risk factors associated with bovine anaplasmosis and how veterinarians can become involved in prevention and control programs for their clients. Education is important because 27% of the survey respondents were not aware of the disease even with a high percentage of herds positive. We also discuss the importance of ensuring appropriate delivery of VFD medication for control of anaplasmosis as part of a control program. Relevant publication:Jones, A. L., Berghaus, R. D., Kalatari, A. A., Credille, B., Naikare, H. K., Heins, B., Saliki, J., & Wilkes, R. P. (2022). Seroprevalence and molecular detection of Anaplasma marginale infected beef herds in Georgia, USA. The Bovine Practitioner, 56(2), 70–78. https://doi.org/10.21423/bovine-vol56no2p70-78
Circulation April 11, 2023 Issue This week, please join author Kavita Sharma and Associate Editor Svati Shah as they discuss the article "Myocardial Metabolomics of Human Heart Failure With Preserved Ejection Fraction." Dr. Greg Hundley: Welcome listeners, to this April 11th issue of Circulation on the Run. And I am one of your cohosts, Dr. Greg Hundley, director of the Pauley Heart Center at VCU Health in Richmond, Virginia. Dr. Peder Myhre: And I am Dr. Peder Myhre from Akershus University Hospital, and the University of Oslo in Norway. Dr. Greg Hundley: Well, Peder, wow. This week's feature discussion, very interesting. We spend a lot of time, especially with our colleague, Dr. Carolyn Lam, on heart failure preserved ejection fraction. But this week's feature discussion, it's going to focus on some of the myocardial metabolomics in this condition. But before we get to that, how about we grab a cup of coffee, and jump into some of the other articles in the issue? How about if I go first? Dr. Peder Myhre: Let's go, Greg. Dr. Greg Hundley: Okay. So Peder, some believe that cardiovascular disease may be the main reason for stagnant growth in life expectancy in the United States since 2010. And so, the American Heart Association, as you know, recently released an updated algorithm for evaluating cardiovascular health. Life's Essential 8, and it has a very nice score. So these authors, led by Dr. Lu Qi, from Tulane University, aimed to quantify the associations of the Life Essential 8 scores with life expectancy in a nationally representative sample of US adults. And the team included 23,000 non-pregnant non- institutionalized participants who were age 20 to 79 years, who participated in the National Health and Nutrition Examination survey, or NHANES, from 2005 to 2018. And whose mortality was identified through linkage to the National Death Index, from the period extending through December of 2019. Dr. Peder Myhre: Oh wow. So really, a validation of the Life's Essential 8. Greg, that's so interesting. What did they find? Dr. Greg Hundley: Right Peder, as you say, very interesting. So here are some of the data, and let's itemize them. So, during a median of 7.8 years of follow up, 1,359 total deaths occurred. Now, the estimated life expectancy at age 50 was 27.3 years, 32.9 years, and 36.2 years, in participants with low Life's Essential 8 scores, less than 50. Moderate, so Life's Essential 8 scores of greater than or equal to 50, but less than 80. And then, high scores, greater than 80. Okay? So equivalently, participants with high Life's Essential 8 scores had an average of 8.9 more years of life expectancy at age 50, compared to those with low scores. Next, on average, 42.6% of the gained life expectancy at age 50, from adhering to sort of that cardiovascular health, those recommendations, was attributable to reduced cardiovascular death. Next, significant associations with the Life's Essential 8 score and life expectancy were observed in both men and women. Next, similarly significant associations of cardiovascular health, Life's Essential 8, with life expectancy were observed in non-Hispanic Whites and non-Hispanic Blacks, but not in those originating from the country of Mexico. So Peder, finally, in summarizing all of this, adhering to the cardiovascular health lifestyle, defined by the Life's Essential 8 score, it was related to a considerably increased life expectancy. However, because of the findings from the individuals from the country of Mexico, more research is needed to be done in some of these minority groups, and particularly, those of Hispanic ethnicity, and perhaps other races. Dr. Peder Myhre: Oh, wow. Very interesting. And I would love to learn more about this subgroup analysis in future studies. So Greg, the next paper is about the hospitalization for heart failure measures. Because contemporary measures of hospital performance for heart failure hospitalization, the 30-day risk standardized readmission and mortality rate, are estimated using the same risk adjusted model and overall event rate for all patients. Thus, the
“You can brush it off or you can speak up for yourself” Kristen has been advocating for herself and others who live with achondroplasia since she was six years old. Kristen joins David Rintell, Head of Patient Advocacy at BridgeBio to tell her personal story about living with achondroplasia and how she became an advocate at just six years old. By third grade, Kristen was speaking to classrooms about what it is like to live with achondroplasia. In the episode, Kristen shares how she has dealt with health issues, overcame adversity and even published her story in the book, Little Legs, Big Heart. She explains that achondroplasia isn’t just about height – there are other important quality of life concerns which she has learned to address, while also helping other families navigate the condition.
Anne Lee, Senior Director of Global Patient Advocacy at BridgeBio, provides an overview of achondroplasia, the most common form of dwarfism. She explains how achondroplasia affects a protein in the body called the fibroblast grown factors receptor 3 or FGFR3, which results in slowing down bone growth. Achondroplasia is the most common cause of disproportionate short stature, affecting approximately 55,000 people in the United States and European Union, including up to 10,000 children and adolescents with open growth plates. Anne talks about her work in patient advocacy and what she has learned by listening to people and families living with achondroplasia.
The paradox of wealth and mental health We are more prosperous, but mentally sicker than ever. Does prosperity bring bad luck? In this podcast Damiaan Denys and Ilse Graat discuss the paradox between greater economic wealth and the increase of mental complaints. Additionally, Damiaan talks about the choices he made as an early career researcher, his professional journey and his reasons to combine philosophy, psychiatry, clinical work and scientific research. One of his research topics focusses on confidence, in this podcast he explains that confidence abnormalities are associated with different psychiatric disorders. Views and opinions expressed in this podcast are those of the interviewee and do not necessarily reflect the official position of ECNP. The content of this podcast should not be used in any way as the basis for treatment decisions.
Kimberly Tableman: Does true transformation in trials start with the clinical protocol? This week we are hosting Kimberly Tableman, Founder and CEO of ESPERO Health, and speak about how clinical trial protocols are being re-imagined in our industry. We dive into what a protocol actually is and what it describes. Protocols are currently being developed with a lot of manual research. WIth googling, phoning friends and re-using existing protocols in word documents. Trials today are being conducted in a more complex environment than before. This means that it is necessary to adapt the trial design as the trial is executed. Creating a trial and executing it unchanged is becoming more rare and requirements for additional digitization in this space are increasing. Trial design is also a very collaborative process involving 10-12 stakeholders. Using a system that supports collaborative creation is key to avoid the pitfalls of versioning and overwriting of comments. Writing the protocol with data collected from the current market can make the protocol more robust and accelerate timelines. That is what Espiro health aims to provide in their protocol platform. Making it easy is the trick to ensure adoption. We also speak about the dynamics that lead to rigidity in the pharmaceutical space and how having sufficient inflow of money in especially big pharma leads to containing the status quo. Speaking out of her experience as a founder, we dive into what it means to start a technology company in the life sciences space and how funding is key to getting off the ground. Guest:Kimberly Tablemanhttps://www.linkedin.com/in/kimberly-tableman/ESPERO Healthhttps://www.linkedin.com/company/espero-health/ ________Reach out to Sam Parnell and Ivanna RosendalJoin the conversation on our LinkedIn page
Safety in the workplace with Jordan Tesluk: Protocols for prevention of tick-borne illnesses in the workplace A growing concern for many outdoor workers across the country is the risk of a tick encounter in their workplace. Fortunately there are steps that employers and employees can take to reduce the risk of tick bites and tick-borne illnesses. Increased awareness is an important first step, and creating and implementing policies in the workplace helps keep employees safe and businesses running efficiently. In this podcast, Sarah is joined by Jordan Tesluk, a Forestry Safety Advocate for silviculture and consultant forestry in British Columbia.
Read the full show notes!
CanLyme Tick Removal Kit
More on tick testing
Mapping ticks in Canada
Industry pricing for tick testing with Geneticks A growing concern for industries and employees across the country is the risk of a tick encounter in the workplace. Both employers and employees can take important steps to raise awareness and reduce the risk of tick bites and tick-borne illnesses. Sarah addresses safety in the workplace in these podcasts with Jordan Tesluk and Tim Tchida. Providing employees with a CanLyme Tick Removal Kit helps to ensure safe and timely tick removal, and testing ticks for pathogens can provide important information regarding potential exposure to those pathogens.Show notes.
 
CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-323
Overview: This episode will explore a common syndrome that is often misdiagnosed and underdiagnosed. Listen in as we discuss the cardinal symptoms” id=”ufOUrAWWyz” vid=”ufOUrAWWyz” id-for-player=”ufOUrAWWyz” link=”/listen/chalk-it-up-to-stress-and-anxiety-or-is-there-more-to-it-frankly-speaking-ep-323-ufOUrAWWyz/” is-authorized=”false” custom-styles=”margin: 0 24px 24px 0;”>
Chalk It Up to Stress and Anxiety or Is There More to It? – Frankly Speaking Ep 323 Credits: 0.25 AMA PRA Category 1 Credit™
 
CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-323
Overview: This episode will explore a common syndrome that is often misdiagnosed and underdiagnosed. Listen in as we discuss the cardinal symptoms and diagnostic criteria for postural orthostatic tachycardia syndrome (POTS) and learn about different management options, including the benefits of salt. 
Episode resource links:
Zha K, Brook J, McLaughlin A, Blitshteyn S. Gluten-free diet in postural orthostatic tachycardia syndrome (POTS). Chronic Illness. 2022;0(0). doi:10.1177/17423953221076984
Cooperrider, J., Kriegler, J., Yunus, S., & Wilson, R. (2022). A Survey-Based Study Examining Differences in Perception of Postural Orthostatic Tachycardia Syndrome Between Patients and Primary Care Physicians. Cureus, 14(10).
Raj, S. R., Fedorowski, A., & Sheldon, R. S. (2022). Diagnosis and management of postural orthostatic tachycardia syndrome. Cmaj, 194(10), E378-E385.
Williams, E. L., Raj, S. R., Schondorf, R., Shen, W. K., Wieling, W., & Claydon, V. E. (2022). Salt supplementation in the management of orthostatic intolerance: Vasovagal syncope and postural orthostatic tachycardia syndrome. Autonomic neuroscience, 237, 102906.


Guest: Mariyan L. Montaque, DNP, FNP-BC
 
Music Credit: Richard Onorato
Is an Uncomplicated UTI Really Uncomplicated? The controversy surrounding whether to collect urine cultures and which empiric treatment to prescribe in patients with uncomplicated UTI has left many clinicians unsure of the right approach. In this the first episode of a podcast series, we’ll discuss the definition of clinical cure and dive into the evidence behind grey areas in the diagnosis and management of uncomplicated UTI.
Disclaimers:
This presentation is sponsored by GSK. The speakers are GSK paid healthcare providers. The content is intended to support disease state education and is considered nonpromotional.
The content and views expressed therein do not necessarily reflect the views, policies, or position of Pri-Med. This program is limited to Health Care Professionals (HCPs) only. GSK complies with all state and federal laws including transparent reporting and disclosure of payments and transfers of value to HCPs.
 
References:
Gupta K, Hooton TM, Naber KG, et al.; Infectious Diseases Society of America; European Society for Microbiology and Infectious Diseases. International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women: A 2010 update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases. Clin Infect Dis. 2011;52(5):e103- e120. doi: 10.1093/cid/ciq2572.
Anger J, Lee U, Ackerman AL, et al. Recurrent uncomplicated urinary tract infections in women: AUA/CUA/SUFU guideline. J Urol. 2019;202(2):282-289. doi: 10.1097/JU.00000000000002963
Houlbar M, Meng L. SHC Clinical Pathway: Inpatient Management of Urinary Tract Infections – Adult Patients. Stanford Antimicrobial Safety and Sustainability Program. November 2017. https://med.stanford.edu/content/dam/sm/bugsanddrugs/documents/c linicalpathways/SHC-UTI-Inpatient-Guideline.pdf. Accessed November 30, 2022.
Hooton TM, Gupta K. Acute simple cystitis in women. UpToDate. Updated March 15, 2021. Accessed November 9, 2022. https://www.uptodate.com/contents/acute-simple-cystitis-in-women
Colgan R, Williams M. Diagnosis and treatment of acute uncomplicated cystitis. Am Fam Physician. 2011;84(7):771-776.
Shafrin J, Marijam A, Joshi AV, et al. Impact of suboptimal or inappropriate treatment on healthcare resource use and cost among patients with uncomplicated urinary tract infection: an analysis of integrated delivery network electronic health records. Antimicrob Resist Infect Control. 2022;11(1):133. Published 2022 Nov 4. doi:10.1186/s13756-022-01170-3
Daneman N, Chateau D, Dahl M, et al. Fluoroquinolone use for uncomplicated urinary tract infections in women: a retrospective cohort study. Clin Microbiol Infect. 2020;26(5):613-618. doi:10.1016/j.cmi.2019.10.016
Bratsman A, Mathias K, Laubscher R, Grigoryan L, Rose S. Outpatient fluoroquinolone prescribing patterns before and after US FDA boxed warning. Pharmacoepidemiol Drug Saf. 2020;29(6):701-707. doi:10.1002/pds.5018
FDA Drug Safety Communication. FDA. 2019. Accessed October 10, 2022 https://www.fda.gov/drugs/drug-safety-and-availability/fda-warns[1]about-increased-risk-ruptures-or-tears-aorta-blood-vessel[1]fluoroquinolone-antibiotics
Nicolle LE; AMMI Canada Guidelines Committee*. Complicated urinary tract infection in adults. Can J Infect Dis Med Microbiol. 2005;16(6):349- 360. doi:10.1155/2005/385768
Patient-Centered Approach to Treating UTIs: Seeking Consensus Through Controversies Uncomplicated UTIs (Urinary Tract Infections) can have a detrimental impact on emotional wellbeing. Patients may feel ignored by their clinicians, who face a diverse set of challenges when managing uncomplicated UTIs, all of which are important to address when keeping the plan patient-centered. In this podcast, we will discuss patient-clinician communication barriers and the importance of patient[1]centered outcomes in managing uncomplicated UTIs.
Disclaimers:
This presentation is sponsored by GSK. The speakers are GSK paid healthcare providers. The content is intended to support disease state education and is considered nonpromotional.
The content and views expressed therein do not necessarily reflect the views, policies, or position of Pri-Med. This program is limited to Health Care Professionals (HCPs) only. GSK complies with all state and federal laws including transparent reporting and disclosure of payments and transfers of value to HCPs.
 
References:
Hilt EE, McKinley K, Pearce MM, et al. Urine is not sterile: use of enhanced urine culture techniques to detect resident bacterial flora in the adult female bladder. J Clin Microbiol. 2014;52(3):871-876. doi:10.1128/JCM.02876-13
Lindsay LE, et al. Clinical Practice Guideline for the Management of Asymptomatic Bacteriuria: 2019 Update by the Infectious Diseases Society of America. Clin Infect Dis 68, no. 10 (May 2, 2019): e83–110. https://doi.org/10.1093/cid/ciy1121
Advani SD, Polage CR, Fakih MG. Deconstructing the urinalysis: A novel approach to diagnostic and antimicrobial stewardship. Antimicrob Steward Healthc Epidemiol. 2021;1(1):e6. doi: 10.1017/ash.2021.167. Epub 2021 Jun 28. PMID: 34604864; PMCID: PMC8486290
FDA Drug Safety Communication. FDA. 2016. Accessed October 10, 2022 https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety[1]communication-fda-advises-restricting-fluoroquinolone-antibiotic-use-certain
Anger J, Lee U, Ackerman AL, et al. Recurrent uncomplicated urinary tract infections in women: AUA/CUA/SUFU guideline. J Urol. 2019;202(2):282-289. doi: 10.1097/JU.00000000000002963
Thompson J, Marijam A, Mitrani-Gold FS, Wright J, Joshi AV. Activity impairment and health-related emotional wellbeing associated with an uncomplicated urinary tract infection among US females. Oral presentation at: IDWeek 2021; September 29-October 3, 2021; Virtual Conference. Session: UTIs; presentation 196
7.Colgan R, Keating K, Dougouih M. Survey of symptom burden in women with uncomplicated urinary tract infections. Clin Drug Investig. 2004;24(1):55-60. doi: 10.2165/00044011-200424010-00007
Thompson J, Marijam A, Mitrani-Gold FS, Wright J, Joshi AV. A survey study of healthcare resource use, and direct and indirect costs, among females with an uncomplicated urinary tract infection in the United States. Poster presented at: IDWeek 2021; September 29-October 3, 2021. Poster 1227
Grigoryan L, Mulgirigama A, Powell M, Schmiemann G. The emotional impact of urinary tract infections in women: a qualitative analysis. BMC Womens Health. 2022;22(1):182. doi: 10.1186/s12905-022-01757-3
Scott VC, Thum LW, Sadun T, et al. Fear and frustration among women with recurrent urinary tract infections: findings from patient focus groups. J Urol. 2021;206(3):688-695. doi: 10.1097/JU.0000000000001843
Lecky DM, Howdle J, Butler CC, McNulty CA. Optimising management of UTIs in primary care: a qualitative study of patient and GP perspectives to inform the development of an evidence-based, shared decision-making resource. Br J Gen Pract. 2020;70(694):e330-e338. doi: 10.3399/bjgp20X708173
Chwa A, Kavanagh K, Linnebur SA, Fixen DR. Evaluation of methenamine for urinary tract infection prevention in older adults: a review of the evidence. Ther Adv Drug Saf. 2019;10:2042098619876749. Published 2019 Sep 23. doi:10.1177/2042098619876749
Harding C, Mossop H, Homer T, etal. Alternative to prophylactic antibiotics for the treatment of recurrent urinary tract infections in women: multicentre, open label, randomised, non-inferiority trial. BMJ 2022;376:e068229. doi: 10.1136/bmj-2021-0068229
Wade C, et al. Methenamine Prophylaxis for Recurrent Urinary Tract Infections in a Tertiary Referral Center. Urol Pract 2021;8(8):699-704
Hoffmann TC. Methenamine hippurate for recurrent urinary tract infections. BMJ 2022; 376
De Paepe H, Hoebeke P, Renson C, et al. Pelvic-floor therapy in girls with recurrent urinary tract infections and dysfunctional voiding. Br J Urol. 1998;81 Suppl 3:109-113. doi:10.1046/j.1464-410x.1998.00021.x
Hooton TM, Vecchio M, Iroz A et al. Effect of increased daily water intake in
Managing Recurrent UTIs: From Prevention to Treatment The complexity behind recurrent UTI management often leaves both patients and clinicians with questions on the optimal management strategy. Should they be treated as an uncomplicated UTI? Are there special considerations or prevention measures? Are there unforeseen or unknown factors contributing to disease incidence? In this second episode, we take a deep dive into the treatment and management of recurrent UTI and explore the impact that this disease has on patients.
Disclaimers:
This presentation is sponsored by GSK. The speakers are GSK paid healthcare providers. The content is intended to support disease state education and is considered nonpromotional.
The content and views expressed therein do not necessarily reflect the views, policies, or position of Pri-Med. This program is limited to Health Care Professionals (HCPs) only. GSK complies with all state and federal laws including transparent reporting and disclosure of payments and transfers of value to HCPs.
 
References:
Anger J, Lee U, Ackerman AL, et al. Recurrent uncomplicated urinary tract infections in women: AUA/CUA/SUFU guideline. J Urol. 2019;202(2):282-289. doi: 10.1097/JU.00000000000002963. 
Foxman B, Brown P. Epidemiology of urinary tract infections: transmission and risk factors, incidence, and costs. Infect Dis Clin North Am. 2003;17(2):227-241. doi: 10.1016/s0891-5520(03)00005-9
Foxman B, Gillespie B, Koopman J, et al. Risk factors for second urinary tract infection among college women. Am J Epidemiol 2000; 151:1194.
Ikäheimo R, Siitonen A, Heiskanen T, et al. Recurrence of urinary tract infection in a primary care setting: analysis of a 1-year follow-up of 179 women. Clin Infect Dis 1996; 22:91.
Gupta K, Hooton TM, Naber KG, et al. International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women: a 2010 update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases. Clin Infect Dis. 2011;52:e103.
Markowitz MA, Wood LN, Raz S, Miller LG, Haake DA, Kim JH. Lack of uniformity among United States recommendations for diagnosis and management of acute, uncomplicated cystitis. Int Urogynecol J. 2019;30(7):1187-1194. doi:10.1007/s00192-018-3750-z.
Labcorp Report – Antibiotic Resistance in Bladder Infections (2019). https://www.labcorp.com/organizations/data/insights[1]analysis#InsightAnalytics-Antibiotic. Accessed December 1, 2022.
Langford BJ, Brown KA, Diong C, et al. The Benefits and Harms of Antibiotic Prophylaxis for Urinary Tract Infection in Older Adults. Clin Infect Dis. 2021;73(3):e782-e791. doi:10.1093/cid/ciab116
Harding C, Mossop H, Homer T, et al. Alternative to prophylactic antibiotics for the treatment of recurrent urinary tract infections in women: multicentre, open label, randomised, non-inferiority trial. BMJ. 2022;376:e068229. Published 2022 Mar 9. doi:10.1136/bmj-2021-0068229
Allergies Are Weird. So Are Cats Katie Wu is a bona fide cat person. She has two of them: twin boys named Calvin and Hobbes. Every night, they curl up in bed with her, bonking their little noses together, rubbing their fur and whiskers everywhere, and leaving behind inevitable cat residue. It's certifiably cute … and a little bit gross.It's also the worst nightmare for the cat-allergic. Which, just shy of a decade ago, Katie was. In a stroke of luck, Katie's debilitating cat allergy disappeared. The reasons for her immune overhaul remain a mystery.Allergies can wax and wane over time, but it seems to be less common to have the night-and-day shift that Katie experienced. In this episode, Katie walks host Aaron Scott through the dynamic world of allergies and what it reveals about our immune systems. And of course, Katie's cats make cameo appearances. (encore)
News Round Up: Mammoth Meatballs, Stressed Plants And Apologetic Robots In this Friday round up of science news we can't let go, not everything is as it seems. Meatballs are not made of fresh meat from the cattle range. Robots are keeping something from you. And plants have secrets they keep out of your earshot. It's deceptive science, Short Wave-style. We love hearing what you're reading and what science is catching your eye! Reach the show by emailing [email protected].
Launching Into Space — Sustainably! In 1957, the Space Age began with the launch of Sputnik, the first artificial satellite. Since then, the number of objects humans have hurled toward the stars has soared to the thousands. As those objects have collided with one another, they've created more space debris in Earth's orbit. According to some estimates, all of that debris and human-made space trash, the number of objects — from satellites to screws — could be in the millions. In this iteration of our AAAS live show series, Short Wave co-host Aaron Scott talks to Danielle Wood, an assistant professor of aeronautics and astronautics at MIT, about the dangers of accumulating space debris, and how she and others are working to make space more sustainable. Have a story about space innovation you'd love us to share? Launch it our way at [email protected].
The Most Common Neurological Disorder Among Young Adults – Multiple Sclerosis This episode is an in depth review of Multiple Sclerosis, The most common neurological disorder among young adults. Multiple Sclerosis is an autoimmune disease of the central nervous system and is one of the most common conditions that is addressed in the field of neurology. Despite the advances in medicine and the emergence of tools to help with diagnosis, it is one of the most common conditions that is misdiagnosed because of its highly variable expression and findings. This can create a unique set of issues for patients, and the goal of this podcast episode is to shed light on the advances in our knowledge of MS, busts some myths regarding the management of MS, which unfortunately is quite common in the wellness space, and to recognize that there are medications, therapies, coping strategies, and support groups to help address these problems. If you or anyone you know is experiencing any of the symptoms, it is important that they speak with a physician,or a nurse or call the National MS Society at 1-800-344-4867.   This episode was a live recording for our NEURO Academy members.  NEURO Academy is a membership based online environment where you’ll have access to resources to achieve optimal health, a better, sharper memory, and prevent cognitive decline, with on demand courses with CE and CME credits and a thriving community. Learn more by visiting NEUROacademy.com. Follow us: Join the NEURO Academy: NEUROacademy.com Follow us on social media: Instagram: The Brain Docs @thebraindocs Facebook: The Brain Docs TikTok: @thebraindocs Website: TheBrainDocs.com
Behind the Article: A Perspective on the Discovery of Enzyme Activators Welcome to the SLAS Discovery Author Insights podcast! Today we are joined by Antonia Turberville and Geoffrey A. Holdgate to discuss their recent perspective article titled "A perspective on the discovery of enzyme activators". This article sheds light on the largely under-explored area of enzyme activation in drug discovery.Despite the successful application of enzyme activators in various therapeutic interventions, the field remains under-represented and poorly exploited. Antonia and Geoffrey delve into the challenges of hit identification for enzyme activation, as well as their perspectives on the approaches needed to overcome these challenges in early drug discovery.Antonia and Geoffrey provide valuable insights into some of the issues and opportunities in enzyme activation, which can be useful for researchers in the field. Join us as we explore this exciting area of drug discovery and gain insights from our experts in the field!  Click here to read the latest articles in SLAS Discovery.Register for the SLAS 2023 Building Biology in 3D Symposium and receive ₤100 off SLAS Europe 2023 Conference and Exhibition full conference registration!20-21 April 2023Cambridge, UK
Cows of the Future Join Tim and Kim and Dr. Francis Fluharty of the University of Georgia  as they talk about changes in cattle over the past 60 years, whether these changes can be sustained in the future, and the desirability of selecting for cows that are excellent swimmers for future floods. ReferencesHerrero, M., & Thornton, P. K. (2013). Livestock and global change: Emerging issues for sustainable food systems. Proceedings of the National Academy of Sciences, 110(52), 20878–20881. https://doi.org/10.1073/pnas.1321844111Lamm, K. W., Randall, N. L., & Fluharty, F. L. (2021). Critical issues facing the animal and food industry: A Delphi analysis. Translational Animal Science, 5(1), txaa213. https://doi.org/10.1093/tas/txaa213Nicol, C. J. (2021). A Grand Challenge for Animal Science: Multiple Goals – Convergent and Divergent. Frontiers in Animal Science, 2, 640503. https://doi.org/10.3389/fanim.2021.640503Nielsen, M. S. W., & Bergfeld, E. (2003). Critical perspectives in animal agriculture: A response. Journal of Animal Science, 81(11), 2908–2911. https://doi.org/10.2527/2003.81112908xRioja-Lang, F. C., Connor, M., Bacon, H. J., Lawrence, A. B., & Dwyer, C. M. (2020). Prioritization of Farm Animal Welfare Issues Using Expert Consensus. Frontiers in Veterinary Science, 6, 495. https://doi.org/10.3389/fvets.2019.00495Schillo, K. K. (2003). Critical perspectives of animal agriculture: Introduction1,2. Journal of Animal Science, 81(11), 2880–2886. https://doi.org/10.2527/2003.81112880x
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S4 Ep14: The Curse of Pocatello Joe returns from S3 Ep17, and brings his wife, Amy, with him, to give updates and to further explain what seems to be some sort of curse or claim that the area of Pocatello has on them and others…
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Sunday Musings Ep17: Holy Week I was blessed with an opportunity to teach about Holy Week at my church, and wanted to share it with you… Happy Resurrection Day! He is Risen! God Bless!



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Transforming the future of point-of-care diagnostics The COVID-19 pandemic has accelerated the adoption of telehealth, vaccine manufacturing, and point-of-care diagnostics, improving patient access to immediate care. In this episode, we welcome Nigel Lindner, the chief innovation officer at LumiraDx, to discuss the transformative impact of point-of-care diagnostics on our health care system. From reducing health inequalities to improving patient outcomes, Nigel explores the ways in which these technologies are revolutionizing health care delivery. He also highlights the importance of scaling up these innovations to reach vulnerable populations and creating a more equitable health care system. Join us as we dive into the future of point-of-care diagnostics and the role it plays in shaping a healthier and more inclusive future. Nigel Lindner is the chief innovation officer, LumiraDx. He shares his story and discusses his KevinMD article, "Immediate, accurate diagnosis is crucial to the future of equitable patient care." The Podcast by KevinMD is brought to you by the Nuance Dragon Ambient eXperience. With a growing physician shortage, increasing burnout, and declining patient satisfaction, a dramatic change is needed to make health care more efficient and effective and bring back the joy of practicing medicine. AI-driven ambient clinical intelligence promises to help by revolutionizing patient and provider experiences with clinical documentation that writes itself. The Nuance Dragon Ambient eXperience, or DAX for short, is a voice-enabled, ambient clinical intelligence solution that automatically captures patient encounters securely and accurately at the point of care. Physicians who use DAX have reported a 50 percent decrease in documentation time and a 70 percent reduction in feelings of burnout, and 83 percent of patients say their physician is more personable and conversational. Rediscover the joy of medicine with clinical documentation that writes itself, all within the EHR. VISIT SPONSOR → https://nuance.com/daxinaction SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended GET CME FOR THIS EPISODE → https://earnc.me/hvSOjm Powered by CMEfy.
Breaking the stigma: Using life coaching to navigate chronic disease Join us with guest Kimberly Jackson-Bekemeier, a family physician with a personal story of managing Type 1 diabetes amidst the pandemic. Kimberly shares her journey of struggling with the diagnosis, feeling lost and alone, until she discovered the power of life coaching. She shares how this process allowed her to take control of her emotions and make a choice to live on her own terms, even with a chronic disease. Kimberly highlights the importance of mental clarity in the medical system and how life coaching provides a space for patients to listen to their thoughts, emotions and facts to ultimately lead to better patient satisfaction and outcomes. Don't miss this inspiring episode as Kimberly sheds light on the human experience and encourages us to explore the other facets impacting our patients and meet them where they are to help them towards where they'd like to go. Kimberly Jackson-Bekemeier is a board-certified family physician and founder, Coaching Chronic Disease, LLC. She can be reached on Facebook and Instagram. She shares her story and discusses her KevinMD article, "A doctor’s journey: Navigating chronic disease and empowerment through life coaching." The Podcast by KevinMD is brought to you by the Nuance Dragon Ambient eXperience. With so many demands on their time, physicians today report record levels of burnout. Burnout is caused by many factors, one of which is clinical documentation. Studies indicate physicians spend two hours documenting care for every hour spent with patients. At Nuance, we are committed to helping physicians do what you love – care for patients – and spend less time on clinical documentation. The Nuance Dragon Ambient eXperience, or DAX for short, is an AI-powered, ambient clinical intelligence solution that automatically captures patient encounters securely and accurately at the point of care. Physicians who use DAX have reported a 50 percent decrease in documentation time and a 70 percent reduction in feelings of burnout, and 83 percent of patients say their physician is more personable and conversational. Rediscover the joy of medicine with clinical documentation that writes itself, all within the EHR. VISIT SPONSOR → https://nuance.com/daxinaction SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended GET CME FOR THIS EPISODE → https://earnc.me/hyciua
Uncovering the hidden causes of Alzheimer's disease Join us on this episode as we welcome Arnold Eiser, an internal medicine physician, as he shares his insights on Alzheimer’s disease. Arnold believes that Alzheimer’s may be largely preventable, despite conventional wisdom suggesting otherwise. He argues that the pathogenesis of Alzheimer’s is largely extracranial and that environmental toxins play a significant role in its development. Arnold has written a book, Preserving Brain Health in a Toxic Age: New Insights from Neuroscience, Integrative Medicine, and Public Health, as well as several scholarly articles, to share his comprehensive view on the complex interactions between gut-brain, liver-brain, gut-immune, endocrine-immune, and nutrient-immune systems. He believes that a Mediterranean or Japanese diet, exercise, avoiding biotoxins and toxicants, and avoiding tobacco and excessive alcohol consumption are key to preventing Alzheimer’s. Tune in to hear Arnold share his ideas on how to preserve brain health and prevent Alzheimer’s. Arnold R. Eiser is an internal medicine physician and author of Preserving Brain Health in a Toxic Age: New Insights from Neuroscience, Integrative Medicine, and Public Health. He shares his story and discusses his KevinMD article, "Challenging conventional wisdom: How to reduce the risk of Alzheimer’s disease." The Podcast by KevinMD is brought to you by the Nuance Dragon Ambient eXperience. With so many demands on their time, physicians today report record levels of burnout. Burnout is caused by many factors, one of which is clinical documentation. Studies indicate physicians spend two hours documenting care for every hour spent with patients. At Nuance, we are committed to helping physicians do what you love – care for patients – and spend less time on clinical documentation. The Nuance Dragon Ambient eXperience, or DAX for short, is an AI-powered, ambient clinical intelligence solution that automatically captures patient encounters securely and accurately at the point of care. Physicians who use DAX have reported a 50 percent decrease in documentation time and a 70 percent reduction in feelings of burnout, and 83 percent of patients say their physician is more personable and conversational. Rediscover the joy of medicine with clinical documentation that writes itself, all within the EHR. VISIT SPONSOR → https://nuance.com/daxinaction SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended GET CME FOR THIS EPISODE → https://earnc.me/HNlW2l Powered by CMEfy.
Overcoming obstacles: Increasing diversity in residency programs In this episode, we're joined by Heidi Chumley, dean at the Ross University School of Medicine, to discuss the barriers facing aspiring physicians in their journey to residency. Heidi will delve into the challenges of the residency matching process, including the cost of applications and travel expenses, as well as bias based on USMLE scores and discrimination in residency programs. She will also discuss the steps her medical school is taking to increase diversity and support its students in their journey to become successful resident physicians. With a 96 percent first-time residency attainment rate, Heidi provides valuable insight into the challenges and solutions in this important aspect of the health care industry. Heidi Chumley is dean, Ross University School of Medicine. She shares her story and discusses her KevinMD article, "Proposing solutions to end bias in the medical residency selection process." The Podcast by KevinMD is brought to you by the Nuance Dragon Ambient eXperience. With so many demands on their time, physicians today report record levels of burnout. Burnout is caused by many factors, one of which is clinical documentation. Studies indicate physicians spend two hours documenting care for every hour spent with patients. At Nuance, we are committed to helping physicians do what you love – care for patients – and spend less time on clinical documentation. The Nuance Dragon Ambient eXperience, or DAX for short, is an AI-powered, ambient clinical intelligence solution that automatically captures patient encounters securely and accurately at the point of care. Physicians who use DAX have reported a 50 percent decrease in documentation time and a 70 percent reduction in feelings of burnout, and 83 percent of patients say their physician is more personable and conversational. Rediscover the joy of medicine with clinical documentation that writes itself, all within the EHR. VISIT SPONSOR → https://nuance.com/daxinaction SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended GET CME FOR THIS EPISODE → https://earnc.me/opt1K1 Powered by CMEfy.
From overworking to self-care: a pediatric neurologist's journey In this episode, we welcome Maria Xiang, a pediatric neurologist, join us to share her personal journey and insights on how to remain emotionally present in the midst of life's challenges. Maria opens up about how she believed that virtue and self-sacrifice were her protection, leading her to overwork and overprepare without considering her own worthiness and fulfillment. She shares how this mindset affected her during her medical training, especially when dealing with her mother's end-stage cancer. She also shares practical tips and strategies she's learned over the years to help her remain emotionally present and connected with her wiser self, including understanding that human needs go beyond just food, shelter, and minimal sleep. Join us in this enlightening conversation as Maria shares her experiences and insights on how to remain emotionally present and honor your human needs, even in the face of life's most difficult challenges. Xinran Maria Xiang is a pediatric neurologist. She shares her story and discusses her KevinMD article, "Finding emotional presence in a dehumanizing system: a physician’s journey." The Podcast by KevinMD is brought to you by the Nuance Dragon Ambient eXperience. With so many demands on their time, physicians today report record levels of burnout. Burnout is caused by many factors, one of which is clinical documentation. Studies indicate physicians spend two hours documenting care for every hour spent with patients. At Nuance, we are committed to helping physicians do what you love – care for patients – and spend less time on clinical documentation. The Nuance Dragon Ambient eXperience, or DAX for short, is an AI-powered, ambient clinical intelligence solution that automatically captures patient encounters securely and accurately at the point of care. Physicians who use DAX have reported a 50 percent decrease in documentation time and a 70 percent reduction in feelings of burnout, and 83 percent of patients say their physician is more personable and conversational. Rediscover the joy of medicine with clinical documentation that writes itself, all within the EHR. VISIT SPONSOR → https://nuance.com/daxinaction SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended GET CME FOR THIS EPISODE → https://earnc.me/K3s3t5 Powered by CMEfy.
Is personalized medicine worth the cost? In this episode, we discuss personalized medicine with guest Ketan Desai, a physician-executive. We explore how Henry Ford's mass production method influenced the pharmaceutical industry, and how personalized medicine presents new challenges. CAR T-cell therapy is an example of personalized medicine, but it cannot be mass-produced and is expensive, costing up to $1 million per patient. We examine the pushback against excessive healthcare spending and how the high cost of personalized medicine may lead to a need for balance between innovation and practicality. Join us as we delve into the future implications of personalized medicine. Ketan Desai is a physician-executive. He shares his story and discusses his KevinMD article, "Can personalized medicine live up to its hype in health care?" The Podcast by KevinMD is brought to you by the Nuance Dragon Ambient eXperience. With so many demands on their time, physicians today report record levels of burnout. Burnout is caused by many factors, one of which is clinical documentation. Studies indicate physicians spend two hours documenting care for every hour spent with patients. At Nuance, we are committed to helping physicians do what you love – care for patients – and spend less time on clinical documentation. The Nuance Dragon Ambient eXperience, or DAX for short, is an AI-powered, ambient clinical intelligence solution that automatically captures patient encounters securely and accurately at the point of care. Physicians who use DAX have reported a 50 percent decrease in documentation time and a 70 percent reduction in feelings of burnout, and 83 percent of patients say their physician is more personable and conversational. Rediscover the joy of medicine with clinical documentation that writes itself, all within the EHR. VISIT SPONSOR → https://nuance.com/daxinaction SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended GET CME FOR THIS EPISODE → https://earnc.me/z39Xts Powered by CMEfy.
When peer review goes wrong: the impact on physicians' civil and constitutional rights Join us for this episode with guest Farid Gharagozloo, a cardiothoracic surgeon, as we discuss the unintended consequences of the Health Care Quality Improvement Act of 1986 (HCQIA). While the act was designed to protect public health and safety by enhancing the peer review process and providing a national repository for reported information regarding medical malpractice payments and adverse actions involving physicians, it has resulted in the deprivation of civil and constitutional rights for physicians. The National Practitioner Data Bank (NPDB) reporting provision violates the Constitution's fifth, eighth, ninth, and tenth amendments. There is a dire need for legal action and a corresponding insurance product to reclaim the constitutional rights for all physicians. Join us as we shed light on these egregious violations of physicians' civil and constitutional rights. Farid Gharagozloo is a cardiothoracic surgeon, professor of surgery, and surgeon-in-chief at the Institute For Advanced Thoracic Surgery, University of Central Florida College of Medicine, and UCF Lake Nona Hospital. He shares his story and discusses the KevinMD article, "Unintended consequences of Health Care Quality Improvement Act: a violation of physicians’ civil and constitutional rights." The Podcast by KevinMD is brought to you by the Nuance Dragon Ambient eXperience. With so many demands on their time, physicians today report record levels of burnout. Burnout is caused by many factors, one of which is clinical documentation. Studies indicate physicians spend two hours documenting care for every hour spent with patients. At Nuance, we are committed to helping physicians do what you love – care for patients – and spend less time on clinical documentation. The Nuance Dragon Ambient eXperience, or DAX for short, is an AI-powered, ambient clinical intelligence solution that automatically captures patient encounters securely and accurately at the point of care. Physicians who use DAX have reported a 50 percent decrease in documentation time and a 70 percent reduction in feelings of burnout, and 83 percent of patients say their physician is more personable and conversational. Rediscover the joy of medicine with clinical documentation that writes itself, all within the EHR. VISIT SPONSOR → https://nuance.com/daxinaction SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast RECOMMENDED BY KEVINMD → https://www.kevinmd.com/recommended GET CME FOR THIS EPISODE → https://earnc.me/qluFyT Powered by CMEfy.
The Diaphragm This week we explore the primary muscle of respiration that separates the thoracic & abdominal cavities. A muscle that was historically thought of as being the seat of the soul. In this podcast, we will dissect out the diaphragm's form, function, innervation, & blood supply. Whilst also explaining the origin of some of the terms we use to describe diaphragm-related structures.
The terms mentioned this week are the diaphragm and phrenic nerves. Costophrenic and costodiaphragmatic angles. The oesophageal hiatus and caval openings. Crura, the xiphisternum, skeletal muscle & somatic nerves.
Expert series: Optimize your performance using CBD Optimal Performance Zurich – OPZ collaborates with Sharon Tsai, founder of True North Labs, to create a CBD-based wellness patch called To the Rescue. This method of CBD delivery is unique and greatly differs from oral-based products such as tincture oils. Each patch is precisely dosed and allows for CBD and other feel good ingredients to be absorbed in the body over a course of 8-12 hours. Listen to learn more about how to use the patch and the best ways to incorporate this fun and effective wellness hack into your daily routine.
 
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Alpex Pharma https://www.alpex.com/ 
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Creativity and passion in science communication (Ep 99) On this episode, we take a break from the regular format to talk with Itai Yanai and Martin Lercher of The Night Science Podcast, a show that explores the creative side of science with guests from across the globe. Itai is a professor in the Department of Biochemistry and Molecular Pharmacology at the NYU School of Medicine, and Martin is a professor in both the Institute for Computer Science and the Department of Biology at Heinrich Heine University Düsseldorf. We had a great time chatting with them about our respective podcast experiences, trading tips and reflecting on our passion for science communication and the ways that it has impacted our own research.
Cover art by Keating Shahmehri
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Listener Mail: Breathe in Union Once more, it's time for a weekly dose of Stuff to Blow Your Mind and Weirdhouse Cinema listener mail…See omnystudio.com/listener for privacy information.
Before You Could Remember, Part 1 Our personal memories only extend back so far in life, and before that, there is a void. Why don’t we remember our early childhood and what does it say about human memory, childhood development and cultural ideas about infants? Robert and Joe explore in this episode of Stuff to Blow Your Mind…See omnystudio.com/listener for privacy information.
The Monstrefact: Chaos Daemons of Nurgle In this episode of STBYM’s The Monstrefact, Robert discusses the chaos daemons of Nurgle from Games Workshop’s Warhammer 40,000 universe… (Part 3 of 4)See omnystudio.com/listener for privacy information.
Before You Could Remember, Part 2 Our personal memories only extend back so far in life, and before that, there is a void. Why don’t we remember our early childhood and what does it say about human memory, childhood development and cultural ideas about infants? Robert and Joe explore in this episode of Stuff to Blow Your Mind…See omnystudio.com/listener for privacy information.
Weirdhouse Cinema: The Neverending Story In this episode of Weirdhouse Cinema, Rob and Joe venture into the 1984 fantasy film “The Neverending Story,” a generation-defining film based on the elegant novel by German author Michael Ende. It’s also a throwback to a time when you could have one guy do most of the creature voices in a film. See omnystudio.com/listener for privacy information.
From the Vault: Plant Memories, Part 2 Do plants remember? Do they communicate? What is the extent of their interaction with their environment? In this classic Stuff to Blow Your Mind series, Robert and Joe dive into the amazing world of plant intelligence research. (originally published 04/14/2022)See omnystudio.com/listener for privacy information.
Friday Five: New Eye Scans Could Show How Fast You're Aging The Friday Five covers five stories in research that you may have missed this week. There are plenty of controversies and troubling ethical issues in science – and we get into many of them in our online magazine – but this news roundup focuses on new scientific theories and progress to give you a therapeutic dose of inspiration headed into the weekend.Here are the stories covered this week:- The eyes are the windows to the soul – and biological aging?- What bean genes mean for health and the planet- This breathing practice could lower levels of tau proteins- AI beats humans at assessing heart health- Should you get a nature prescription?Leaps.org is a not-for-profit initiative that publishes award-winning journalism, popularizes scientific progress on social media, and hosts events about bioethics and the future of humanity. Visit the platform at www.leaps.org. Podcast host Matt Fuchs is editor-in-chief of Leaps.org.
Scratching That Itch: Dr. Rachel Asiniwasis Targets Atopic Dermatitis When Dr. Rachel Asiniwasis returned to the prairies after her dermatology residency in Toronto, she noticed a pattern among many of her pediatric patients.   Hundreds of them were coming to her with itchy, raw patches of skin, the result of atopic dermatitis — eczema.   “One of the biggest frustrations for me is when people say ‘oh, it’s just a skin problem’,” said Asiniwasis. “Itching in many ways is just as impactful as chronic pain,”   Atopic dermatitis is the most common chronic skin inflammatory disease. The vast majority of cases start in children under the age of five. At least one in every ten Indigenous children in Canada has some form of eczema. That figure rises to one in every four children in some Arctic communities.   "It is very, very impactful on multiple holistic levels,” said Asiniwasis, who said the itch and pain — amongst other signs and symptoms in moderate to severe cases — can lead to depression, ADHD, anxiety, and an increased risk of suicide.   “A lot of people learn to just live with this condition. If it's not optimally treated, you might see them have hospital visit for flares or secondary infection. And if, for example, if a child has severe disease and it's not controlled and they're not sleeping, that can affect their academic performance. So with eczema, it can get so bad that you can't sleep.”   In this episode, Asiniwasis admits she was late in choosing her specialty, only moving toward dermatology during her second year of medical school, after she met Dr. Peter Hull.   “I had a misconception that it was a scientist that just made things like sunscreens in a lab,” she said. “He was the one who first exposed me to dermatology as being a manifestation of internal and external health.”   The prevalence of atopic dermatitis in her young Indigenous patients soon left her with more questions than answers. Shortly after the Covid-19 pandemic began, she enrolled at the University of George Washington D.C. to earn her master’s degree in clinical and translational research.    Two years ago, she conducted a survey of 50 dermatologists, nurses and family physicians who work in Indigenous communities across Canada. Atopic dermatitis was the most common skin disease reported by their patients, followed by bacterial infections. Other areas of interest observed by participants included, acne/rosacea, scabies, and Hidradenitis suppurativa. Asiniwasis presented her initial findings at the Saskatchewan Health Research showcase.    Working with medical leaders in five southern Saskatchewan Indigenous communities, Asiniwasis was also granted permission and ethics board approval to perform a confidential chart review for hundreds of pediatric patients with atopic dermatitis. A number of those patients saw their uncontrolled atopic dermatitis devolve into secondary infections, often leading to hospital visits and multiple courses of antibiotics.   Asiniwasis hopes to publish her systematic scoping review of North American Indigenous Skin Disease by the end of this year.    "The literature's also showing high rates of bacterial skin infections, which is another part of the scoping review,” she said. “We're also seeing problems with chronic impetigo, boils, MRSA, all of these types of bacterial skin infections in those with uncontrolled eczema in rural and indigenous children, across all fronts.”   She’s seen a number of patients with skin lichenification: something she refers to as ‘elephant skin’.    “It comes to a point where often our first line topical therapies don't penetrate and treat it, or it can take months,” she said. “We have to escalate therapy in these patients, so that can put them at risk for other side effects. We need to prescribe things like immunosuppressants, like methotrexate, or biologic targeted therapy if it's all over the skin. They can't be put in creams everywhere."   She also said doctors need to consider a patient’s needs. Although most would never prescribe only a week’s worth of insulin or heart medication, she often sees them dispense topical ointments for moderate to severe skin disease in small tubes.    "I always say tubs not tubes,” said Asiniwasis. "Give them enough so they're not driving back or undertreating themselves."   After Asiniwasis asked her young patients and their caregivers to describe barriers to healing their skin, they spoke of long wait times to see dermatologists, often travelling hundreds of kilometres at their own cost to seek care.    They also described the cost of skin care products in northern communities as ‘hyper-inflated’. Her patients and their families also face a sharp learning curve, as they adhere to strict bathing regimens, moisturizing, recognizing signs of infection, and learning to us
The Changing Biotech Business and Big Data Ecosystem – Dr. Jeffrey Reid, Regeneron In a rapidly changing technology environment, how do established businesses tackle smart growth and continue transformative change?  In this special edition of Talking Biotech Podcast we examine the business climate of Regeneron, and how growth in the era of genomics and massive data sets from human health changed the process of drug discovery, but also changed how the company would respond to new opportunities and challenges. Dr. Jeffery Reid, Chief Data Officer, explains where the company was, and how it has changed with the rocketing pace of data acquisition and integration.
Countering Livestock mRNA Vaccine Disinformation – Drs. Alison Van Eenennaam and Terry Lehenbauer The COVID pandemic accelerated development of a new class of vaccines. This class, called mRNA vaccines, allows ease in manufacture, rapid response to disease or disease variants, and many other benefits.  But just like any technology, an industry has arisen to stand in its way, promoting false information that painfully mischaracterizes what these new veterinary tools truly are. A cadre of internet personalities now capitalizes off of the manufactured fear that can help farmers, consumers and the environment– as well as fortify animal welfare.  University of California scientists Dr. Alison Van Eenennaam and Dr. Terry Lehenbauer discuss what the mRNA vaccines are, and how efforts to oppose them defy science, especially when codified into law by clueless politicians.
39. Improving Black Women's Health April is National Minority Health Month, and this episode we're sitting down with Dr. Melody McCloud to discuss the health threats faced by minority women—Black women in particular—as well as the vital role of equity in public health. Dr. McCloud is an obstetrician-gynecologist who became the first black woman to establish an OB-GYN practice in DeKalb County, Georgia. Dr. McCloud is also the founder and medical director of Atlanta Women's Healthcare PC and lectures nationwide on women's health, sex and social issues. Her recent book, entitled Black Women's Wellness: Your "I've Got This!" Guide to Health, Sex, and Phenomenal Living, was released in January. This month's episode is hosted by Dr. Judy Monroe, president and CEO of the CDC Foundation. For full episode transcription, visit Contagious Conversations.   Key Takeaways: 1:40] Dr. McCloud talks about her life journey and what drew her to the field of medicine. [3:28] What are some of the most significant physical health threats faced by minority women, and what effect do societal stresses have on black women’s physical health? [4:55] Dr. Monroe and Dr. McCloud discuss homicide as the sixth leading cause of death among Black people. [6:00] Dr. McCloud speaks of the journey of writing her book. [7:49] What changes has Dr. McCloud seen in maternal health outcomes? [10:22] What are the most important steps that women, particularly minority women, can take to improve their health and well-being? [13:06] Why is it essential that we focus on health equity? Where can this focus lead us in public health? [15:29] Dr. McCloud addresses implicit racial bias. [16:15] Dr. McCloud speaks of the societal stress black women experience. [17:19] What bright spots does Dr. McCloud see in public health related to women?   Mentioned in This Episode: Black Women's Wellness: Your "I've Got This!" Guide to Health, Sex, and Phenomenal Living Learn more about the CDC Foundation’s Health Equity work
S09 E07 Sustainability, Accessibility, and Optimal Patient Outcomes Pamela Fralick, President of Innovative Medicines Canada, talks about innovative funding models, working with all levels of the Canadian government, and developing the life sciences sector. Get full access to NPC Healthbiz Weekly at healthbiz.substack.com/subscribe
Health Disparities in Obstructive Sleep Apnea – Prevalence and Diagnosis Register now for ATS 2023 in Washington, D.C.Get ready for a series of dynamic scientific programming with presentations covering the basic sciences, research breakthroughs and clinical treatment!This podcast is a discussion with Dr Susan Redline, Professor of Sleep Medicine at Brigham and Women's Hospital about the current burden of health disparities among Obstructive sleep apnea patients. Spotlight placed on etiological ,pathophysiological and clinical differences among various racial, gender groups along with their clinical implications. Dr Redline's perspective on long term outlook regarding diagnostic modalities used routinely in Sleep practices and future direction of sleep research are discussed.
Health Disparities in Obstructive Sleep Apnea – Treatment Challenges Register now for ATS 2023 in Washington, D.C.Get ready for a series of dynamic scientific programming with presentations covering the basic sciences, research breakthroughs and clinical treatment!In this podcast episode, Dr Ashesha Mechineni interviews Dr Bharati Prasad, Associate Professor of Medicine and Medical Director of UIC Sleep Science Center and Program Director of Sleep fellowship at University of Illinois at Chicago. This is the conclusion of our core discussion on Health Disparities in Obstructive Sleep Apnea. Dr Prasad explains how Positive airway pressure treatment variables vary across various treatment groups and how real life factors play a role in overall long term clinical outcomes. She explores variations in research results among COVID 19 pandemic patients with obstructive sleep apnea as she draws to a close.
#21 A Novel Way To Decrease the Amount of Inappropriate Urine Cultures Ordered In this episode, Drs Krouss and Cho describe an intervention they did to decrease the amount of inappropriate urine cultures being ordered. They share with our audience how unnecessary urine cultures can lead to overdiagnosis and overtreatment of asymptomatic bacteriuria. Their novel approach to fixing the problem consists of a change to the ordering screen in the electronic medical record which requires entry of the reason for the urine cultures and a Best Practice Advisory (BPA) that appears when urine cultures are ordered for a patient. Their intervention resulted in significant decrease of unnecessary urine cultures. Tune in to this must hear episode! With special guests: Mona Krouss, MD Assistant Vice President for Value & Patient Safety for NYC Health + Hospitals and Harry (Hyung Jin) Cho Vice President of Quality at Brigham and Women's Hospital and faculty at Harvard School of Medicine
Circulation March 28, 2023 Issue This week, please join author Vincent Aengevaeren and Associate Editor Jarett Berry as they discuss the article "Exercise Volume Versus Intensity and the Progression of Coronary Atherosclerosis in Middle-Aged and Older Athletes: Findings From the MARC-2 Study." Dr. Gregory Hundley: Welcome listeners to this March 28th issue, and I am one of your co-hosts, Dr. Gregory Hundley, Associate Editor and Director of the Pauley Heart Center at VCU Health in Richmond, Virginia. Dr. Peder Myhre: And I'm Dr. Peder Myhre, Social Media Editor from Akershus University Hospital and University of Oslo in Norway. And today, Greg, we have such an interesting feature paper. It comes to us from Professor Aengevaeren and it discusses the progression of coronary atherosclerosis in middle-aged and older athletes. They're looking at exercise volume versus intensity in the MARC-2 study. So Greg, this is really something us master athletes are interested in, and I'm really excited to hear this discussion. Dr. Gregory Hundley: Very nice. Well, how about we jump into some of the other articles first, Peder? And I could go first. So Peder, my first article involves pregnancy related complications. And as you know, these pregnancy complications are associated with increased risk of developing cardiometabolic diseases and an earlier mortality. However, much of the prior research has been limited to individuals of White race. So these investigators led by Professor Cuilin Zhang from the National Institutes of Health aimed to investigate pregnancy complications in association with total and cause specific mortality in a racially diverse cohort, and then evaluate whether associations differ between Black and White individuals. And they performed their work using the Collaborative Perinatal Project, which was a prospective cohort study of 48,197 pregnant women across 12 US clinical centers from the period of time of 1959 through 1966. Dr. Peder Myhre: Oh wow, Greg. Almost 50,000 pregnant women. Very huge initiative. So what did they find? Dr. Gregory Hundley: Right, Peder. So overall, 15% of participants had preterm delivery, 5% had hypertensive disorders of pregnancy, and 1% had gestational diabetes or impaired fasting glucose. Now, the preterm delivery was higher in individuals of Black race at 20% relative to those of White race, which were 10%. Now, in relation to all-cause mortality, the following were associated with increase adjusted hazard ratios. One, spontaneous labor; two, induced labor; three, pre-labor cesarean delivery. And all of those, those adjusted hazard ratios in comparison with a full term delivery. Next, in the world of blood pressure, preeclampsia and eclampsia as well as superimposed preeclampsia and eclampsia were all associated with adjusted hazard ratios that were elevated compared to individuals with normal blood pressure. And then finally, in those individuals with gestational diabetes or impaired fasting glucose, their adjusted hazard ratio, again for all-cause mortality, was elevated relative to those with normal glycemia. Now interestingly, in comparing the two racial groups, preterm induced labor was associated with greater mortality risk among those of Black race relative to those of White race. However, or while, preterm pre-labor cesarean delivery interestingly and conversely was associated with a higher adjusted hazard ratio for those of White race as compared to individuals of Black race. So Peder, in summary, within this large diverse US cohort, pregnancy complications were associated with higher mortality almost 50 years later. And the higher incidents of some complications occurred in individuals of Black race. And differential associations with mortality risk indicate that because of these racial differences, there could really be disparities in pregnancy related health. And finally, that these disparities and their relationship with overall health really could have long life implications for earlier mortality in these patients. Dr. Peder Myhre: Well, that is really interesting, Greg. Are you ready for the next paper? Dr. Gregory Hundley: Absolutely. Dr. Peder Myhre: So this paper is about the glucagon-like peptide-1 receptor agonist and large CV outcome
Circulation April 4, 2023 Issue This week, please join authors Tatsuhiko Naito and Kosuke Inoue as well as Associate Editor Wendy Post as they discuss the article "Genetic Risk of Primary Aldosteronism and Its Contribution to Hypertension: A Cross-Ancestry Meta-Analysis of Genome-Wide Association Study." Dr. Greg Hundley: Welcome listeners, to this April 4th discussion of Circulation on the Run. I am one of your co-hosts, Dr. Greg Hundley, Associate Editor, Director of the Pauley Heart Center at VCU Health in Richmond, Virginia. Dr. Peder Myhre: And I'm Dr. Peder Myhre from Akershus University Hospital and the University of Oslo in Norway. So Greg, today we have the feature paper, discussing the genetic risk of primary aldosteronism and its contribution to hypertension. So this is such an interesting topic and av very important cost on hypertension. And in this paper, they use cross-ancestry meta-analysis from GWAS studies to assess this very interesting discussion. But first, Greg, I have a paper that comes to us from the DELIVER trial, and it is about dapagliflozin to patients with HFpEF, and assessing the association with the duration of the heart failure. So Greg, it is important to understand how the effects of new treatments vary by the duration of heart failure. Because on one hand, physicians may think that a patient who has longer standing heart failure represents a stable survivor where new treatment is unnecessary. On the other hand, the view has been expressed that patients with long-standing heart failure may have more advanced disease, and there may come a point where they no longer respond to or tolerate the addition of new therapies, particularly because of hypotension, kidney dysfunctional and electrolyte abnormality. So the investigators from the DELIVER trial, led by corresponding all author John McMurray from University of Glasgow, therefore, aimed to assess the efficacy and safety of the SGLT2 inhibitor dapagliflozin, according to the duration of heart failure with EF above 40%. So that is mildly reduced or preserved. Dr. Greg Hundley: Wow, Peder, very timely, very timely article. So what did they find? Dr. Peder Myhre: So Greg, the authors categorized patients by duration of heart failure, one category less than six months, and then six to 12 months, and then one to two years, two to five years, and finally, more than five years. And longer duration heart failure patients were older, and more comorbid with worse symptoms, and the rate of the primary outcome increased with heart failure duration. And so, the benefit of dapagliflozin was consistent across heart failure duration categories with hazard ratios 0.67, 0.78, 0.81, 0.97, and 0.78. And that gives a P4 interaction of 0.41. So the absolute benefit was therefore since there was no P4 interaction, greatest among those with highest risk, and that it was the longest duration heart failure. So there was a number needed to create for heart failure above five years of 24, versus 32 for those with the shortest duration of heart failure. And the authors therefore conclude, that even in patients with long-standing heart failure and generally mild symptoms cannot be considered stable, and it is not too late for such patients to benefit from an SGLT2 inhibitor. Dr. Greg Hundley: Ah, very practical information, Peder, beautiful description. Well Peder, this next paper comes to us evaluating low density lipoprotein cholesterol. And as you know, low density lipoprotein cholesterol is an important causal risk factor for atherosclerotic cardiovascular disease. However, a sizable proportion of middle-aged individuals have not developed coronary atherosclerosis as assessed by the presence of coronary artery calcification. Now whether the presence of coronary artery calcification modifies the association of LDL cholesterol with atherosclerotic cardiovascular disease risk, well, that's unknown. So these authors, led by the corresponding author of Martin Mortensen from Aarhus University Hospital, evaluated the association of LDL cholesterol with future atherosclerotic cardiovascular disease events, in patients with and without coronary artery calcium, from 23,132 consecutive symptomatic patients evaluated for coronary artery disease, using coronary commuted tomography angiography, or CTA, that were included in the Western Denmark Heart Registry, which is a semi-national multi-center based registry with longitudinal registration of both patient and procedural data.</







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190. Mailbag: Can I blend art with science? It’s time to open the listener mailbag to answer your question about the human side of science, and life in the lab! This week: the importance of lunch, blending art with science, and the dream of a lab-based sitcom.







We didn’t have to dig very deep into to the mailbag this week because we heard from an undergraduate listener Monika. She asked a series of questions that covered so much ground, we devote the entire episode to her!



Her first question is about disordered eating, and how lab schedules might interfere with getting three square meals each day. She writes:




For the past year, I’ve been working in a lab with a grad student advisor, and was working there over the summer over 40 hours a week. However, in that entire time, I don’t think I’ve ever seen my advisor eat a meal, and I found that a lot of the time when I asked to take meal breaks it was seen with a sense of inferiority or “weakness” for taking time away from work. I definitely understand that food is not allowed inside of a lot of lab settings for safety reasons, but it was a bit alarming for me to see how little people in this kind of research slip into some unsettling habits like replacing meals with coffee or just skipping meals entirely. I feel like the grad student trope are just so busy that they don’t have time to consider proper nutrition, but as someone who has struggled with disordered eating and eating disorders, this is something I can’t compensate for, if that makes any sense. What are your thoughts about this?




It can definitely be alarming to see students or faculty ‘working through lunch’ because they’re too busy to stop. Long term, that habit is harmful to your mental and physical health, and no job is worth sacrificing those things.



We do our best to reassure Monika that skipping lunch is not pervasive in research labs. In fact, Dan took extra long lunches everyday just to get out of the lab! More seriously, though, you may not see your lab mates eating for a variety of reasons, but that doesn’t mean they’re not finding time to grab a bite.



Next up, we talk scholarships and fellowships:




What are your thoughts about the big research scholarships during undergrad like Goldwater, or postgrad like Rhodes, Marshall, Mitchell, etc.? Are they necessary for getting into grad school? How well would they distinguish an applicant (or not)?




We recently spoke with Elizabeth Somsen about her experience with the Fulbright Scholarship. She studied abroad in Turkey after graduating from college and before entering a PhD program. She’s written a helpful guide to Postbac experiences which is a great place to start your research.



To answer the question more directly, having these experiences on your CV is a wonderful booster, but it’s neither necessary, nor sufficient. Applicants will be judged mostly on their research experience and letters of recommendation.



If you have NO research experience, a postbac is not enough to secure your position. And if you have lots of quality research under your belt, a postbac looks great but is certainly not required.



Next, we discuss the intersection of art and science:




 I am hoping to double major in Film/Media along with a STEM major, as I really love art and science, and want to find a way to do both. I’ve recently been accepted into a study abroad program where I’ll be taking classes at a nationally-ranked film school and doing an entir…
Medicine Unboxed: Where arts and medicine meet Dr. Sam Guglani, an oncologist from Cheltenham, UK, has been running Medicine Unboxed for ten sold-out years. His show examines the interface between medicine, philosophy, and the humanities through a series of speakers and performances. Here, he joins Gavin to discuss philosophy, "good medicine", and the show's move to London. Find out more about Medicine Unboxed here:https://voices.medicineunboxed.org/
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