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Episode 189: Understanding Autophagy and Increasing Your Longevity with Dr Elena Seranova

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Pushing The Limits
01:04:44
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From our physical appearance to our body's mechanical functions, our whole being is encoded into our genes and kept in each cell that makes us. These basic biological units have their system to keep everything functioning and our body alive and moving. They have housekeeping functions: cells perform autophagy to get rid of accumulated waste materials. Maximising the effects of these processes can help in increasing your longevity. When the autophagic processes fail, it can damage important parts of the cell such as the DNA and accelerate ageing. In this episode, Dr Elena Seranova explains the science behind autophagy and how it connects to NAD and sirtuin genes. She also shares her own experience and research on using this knowledge to live a longer, fuller life. Join us in this episode to learn more about autophagy and how this process is useful in increasing your longevity and giving you a boost in life.   Get Customised Guidance for Your Genetic Make-Up For our epigenetics health program that is all about optimising your fitness, lifestyle, nutrition and mind performance to your particular genes, go to https://www.lisatamati.com/page/epigenetics-and-health-coaching/. You can also join our free live webinar on epigenetics.   Online Coaching for Runners Go to www.runninghotcoaching.com for our online run training coaching.   Consult with Me If you would like to work with me one to one on anything from your mindset, to head injuries, to biohacking your health, to optimal performance or executive coaching, please book a consultation here: https://shop.lisatamati.com/collections/consultations.    Order My Books My latest book Relentless chronicles the inspiring journey about how my mother and I defied the odds after an aneurysm left my mum Isobel with massive brain damage at age 74. The medical professionals told me there was absolutely no hope of any quality of life again, but I used every mindset tool, years of research, and incredible tenacity to prove them wrong and bring my mother back to full health within 3 years. Get your copy here: http://relentlessbook.lisatamati.com/  For my other two best-selling books Running Hot and Running to Extremes, chronicling my ultrarunning adventures and expeditions all around the world, go to https://shop.lisatamati.com/collections/books.    Here are three reasons why you should listen to the full episode: Discover how cells stay healthy. Find out Dr Elena's tips and advice in increasing your longevity by activating autophagy. Learn more about the science behind NMN supplements and their revitalising effect.   Resources Read about Dave Asprey’s work around the keto diet. Lifespan by Dr David Sinclair Pushing the Limits Ep 170: The Search for the Perfect Protein with Dr David Minkoff Visit NMNBio if you want to learn more about NMN supplements in New Zealand.   Episode Highlights [04:33] Getting to Know Dr Elena Seranova Dr Elena Seranova is an interdisciplinary scientist.  She holds a degree in Psychology, MSc Translational Neuroscience, and a PhD focusing on autophagy and cell biology. With her expertise in her field, she co-founded a biotech startup and is now the the founder of NMN Bio in the United Kingdom.  [06:06] What Is Autophagy? Autophagy is a catabolic pathway that degrades unwanted materials within the cell. The cell needs to avoid the build-up of unnecessary materials. There are different pathways for activation like mTOR (mammalian target of rapamycin) and PI3K (Phosphoinositide 3-kinase). Impairments at various stages of autophagy lead to
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