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The breadth of scope of stem cell therapies in treating intractable conditions

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STEAM Powered speaks with Assoc Professor Rebecca Lim, stem cell biologist, on using stem cell therapies to treat intractable conditions such as acute ischemic stroke, Crohn's disease, and bronchopulmonary dysplasia.
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when you collect that data and you present that to a human ethics committee and they're convinced and you get the okay to now help patients who are incredibly ill. Um it's yeah, it's really rewarding the diseases that we're going after as well are intractable diseases. I should have mentioned that upfront. We don't go after disease indications where they can be treated using contemporary measures. So, for instance, one of the things that we're looking at is acute ischemic stroke. So if after the 3 to 6 hour period and a clot buster cannot be administered, there's virtually nothing you can do for those stroke patients and those are the types of stroke patients were going after where nothing else can be done. And there is an opportunity for us to make a difference. Um and another disease that we're going after is cartoons related periodical fistulas. And this is a debilitating disease in people who are young. You know, people in their twenties thirties, forties who should have good functioning bodies. And because of Crohn's disease, they can't. Um so we're working with a bunch of colorectal surgeons to see if self therapy could be the way to go for those patients who you're covering quite a few areas with the research at the moment. Yeah. So the it might seem strange initially that we're going across from, you know, very premature babies with francophonie display at one end to disease sort of like in the twenties to forties and then two stroke at the other end of the spectrum. But underlying all of those conditions is inflammation that is not addressed with anti inflammatories. So you can't give an anti inflammatory and have the disease actually calmed down. Um All of those diseases are extremely complex. There is a need to create blood flow across all of those diseases. Um and there is an opportunity to reactivate the stem cells that are already in the tissues that are affected, bearing in mind that every tissue has your own stem cells. So we're proposing that the cells that we transplant will turn into new tissue. What we're saying is that they will go into those tissues and actually reactivate all of those processes and in that again. Yeah, exactly. So that's that's kind of how it's kind of gotten to the breath that it has.